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Federal
Gene expression neighborhoods
U.S. Department of Health & Human Services —
The finding that neighboring eukaryotic genes are often expressed in similar patterns suggests the involvement of chromatin domains in the control of genes within a... -
Federal
Preoperative prediction of pediatric patients with effusions and edema following cardiopulmonary bypass surgery by serological and routine laboratory data
U.S. Department of Health & Human Services —
Aim Postoperative effusions and edema and capillary leak syndrome in children after cardiac surgery with cardiopulmonary bypass constitute considerable clinical... -
Federal
The (CTG)n polymorphism in the NOTCH4 gene is not associated with schizophrenia in Japanese individuals
U.S. Department of Health & Human Services —
Background The human NOTCH4 gene is a candidate gene for schizophrenia due to its chromosomal location and neurobiological roles. In a British linkage study, NOTCH4... -
Federal
Long termin-vivostudies of a photo-oxidized bovine osteochondral transplant in sheep
U.S. Department of Health & Human Services —
Articular cartilage has limited capacity to repair. Defects greater than 3 mm heal with formation of inferior fibrous cartilage. Therefore, many attempts have been... -
Federal
Physiological function of the maltose operon regulator, MalR, in
U.S. Department of Health & Human Services —
Background Maltose metabolism is initiated by an ATP-dependent permease system in Lactococcus lactis. The subsequent degradation of intracellular maltose is performed... -
Federal
Clonal expansion is a characteristic feature of the B-cell repertoire of patients with rheumatoid arthritis
U.S. Department of Health & Human Services —
The present study was designed to analyze the level of B-cell clonal diversity in patients with rheumatoid arthritis by using HCDR3 (third complementarity determining... -
Federal
Assessment of the usefulness of a diagnostic test: A survey of patient preference for diagnostic techniques in the evaluation of intestinal inflammation
U.S. Department of Health & Human Services —
Background In order to assess the usefulness of radiolabeled white cell scanning in the diagnosis of intestinal inflammation, subjects were asked to rank several... -
Federal
Nutrition in the intensive care unit
U.S. Department of Health & Human Services —
Nutritional support has become a routine part of the care of the critically ill patient. It is an adjunctive therapy, the main goal of which is to attenuate the... -
Federal
High-susceptibility of photosynthesis to photoinhibition in the tropical plant
U.S. Department of Health & Human Services —
Background The tropical plant Ficus microcarpa L. f. cv. Golden Leaves (GL) is a high-light sensitive tropical fig tree in which sun-leaves are yellow and shade-... -
Federal
Influence of CSP 310 and CSP 310-like proteins from cereals on mitochondrial energetic activity and lipid peroxidation
U.S. Department of Health & Human Services —
Background The development of chilling and freezing injury symptoms in plants is known to frequently coincide with peroxidation of free fatty acids. Mitochondria are... -
Federal
Arterial indications for the low molecular weight heparins
U.S. Department of Health & Human Services —
Antithrombotic treatment is of proven importance in patients with acute coronary syndromes. There is now accumulating evidence from several clinical trials in... -
Federal
Muscle Specific Fragile X Related Protein 1 Isoforms are Sequestered in the Nucleus of Undifferentiated Myoblast
U.S. Department of Health & Human Services —
Background The family of Fragile X Mental Retardation Proteins is composed of three members: Fragile Mental Retardation 1, Fragile X Related 1 and X Related 2... -
Federal
The molecular mechanism of osteoclastogenesis in rheumatoid arthritis
U.S. Department of Health & Human Services —
Bone-resorbing osteoclasts are formed from hemopoietic cells of the monocyte–macrophage lineage under the control of bone-forming osteoblasts. We have cloned an... -
Federal
Measurement of endotoxin activity in critically ill patients using whole blood neutrophil dependent chemiluminescence
U.S. Department of Health & Human Services —
Background Lipopolysaccharide (endotoxin) from the cell wall of Gram-negative bacteria is a potent trigger for the release of host-derived inflammatory mediators. The... -
Federal
Importance of lysosomal cysteine proteases in lung disease
U.S. Department of Health & Human Services —
The human lysosomal cysteine proteases are a family of 11 proteases whose members include cathepsins B, C, H, L, and S. The biology of these proteases was largely... -
Federal
Emerging strategies of bone and joint repair
U.S. Department of Health & Human Services —
The advances in biomedicine over the past decade have provided revolutionary insights into molecules that mediate cell proliferation and differentiation. Findings on... -
Federal
Utility of routine chest radiographs in a medical–surgical intensive care unit: a quality assurance survey
U.S. Department of Health & Human Services —
Objective To determine the utility of routine chest radiographs (CXRs) in clinical decision-making in the intensive care unit (ICU). Design A prospective evaluation... -
Federal
Where is biological therapy going?
U.S. Department of Health & Human Services —
The substantial progress in our understanding of molecular and cellular biology has allowed us to design biological therapeutics ('biologicals') with defined targets... -
Federal
Feasibility of using quadriceps-strengthening exercise to improve pain and sleep in a severely demented elder with osteoarthritis – a case report
U.S. Department of Health & Human Services —
Background Osteoarthritis (OA) of the knee, which is prevalent among older adults in nursing homes, causes significant pain and suffering, including disturbance of... -
Federal
Detection and characterization of the
U.S. Department of Health & Human Services —
Background Virulence genes on Salmonella pathogenicity island 1 (SPI1) are coordinately regulated by HilA, a member of the OmpR/ToxR family of transcription factors....