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Federal
Blog | Help Shape New Directions in Open Science: Vote for Your Favorite Innovation!
U.S. Department of Health & Human Services —
This blog. post was posted by Elizabeth Kittrie on January 5, 2017. -
Federal
Effect of vitamin D on bone mineral density of elderly patients with osteoporosis responding poorly to bisphosphonates
U.S. Department of Health & Human Services —
Background Bisphosphonates are indicated in the prevention and treatment of osteoporosis. However, bone mineral density (BMD) continues to decline in up to 15% of... -
Federal
Efficacy ofHelicobacter pylorieradication therapies: a single centre observational study
U.S. Department of Health & Human Services —
ManyHelicobacter pylorieradication regimens have been described. There are little data reporting their efficacy or integration in routine clinical practice. The... -
Federal
Stratum corneum lipids liposomes for the topical delivery of 5-aminolevulinic acid in photodynamic therapy of skin cancer: preparation and in vitro permeation study
U.S. Department of Health & Human Services —
Background Photodynamic therapy (PDT) using 5-aminolevulinic acid (5-ALA) is a skin cancer therapy that still has limitations due to the low penetration of this drug... -
Federal
Antibodies against prM protein distinguish between previous infection with dengue and Japanese encephalitis viruses.
U.S. Department of Health & Human Services —
Background In Southeast Asia, dengue viruses often co-circulate with other flaviviruses such as Japanese encephalitis virus, and due to the presence of shared... -
Federal
Antenatal screening and its possible meaning from unborn baby's perspective
U.S. Department of Health & Human Services —
In recent decades antenatal screening has become one of the most routine procedure of pregnancy-follow up and the subject of hot debate in bioethics circles. In this... -
Federal
The alpha/beta fold uracil DNA glycosylases: a common origin with diverse fates
U.S. Department of Health & Human Services —
Background: Uracil DNA glycosylases (UDGs) are major repair enzymes that protect DNA from mutational damage caused by uracil incorporated as a result of a polymerase... -
Federal
Modulation of cathepsin G expression in severe atopic dermatitis following medium-dose UVA1 phototherapy
U.S. Department of Health & Human Services —
Background During the last decade, medium-dose UVA1 phototherapy (50 J/cm2) has achieved great value within the treatment of severe atopic dermatitis (AD). The... -
Federal
Plant growth regulatory effect and insecticidal activity of the extracts of the Tree of Heaven (
U.S. Department of Health & Human Services —
Background There is an urgent need to explore and utilize naturally occurring products for combating harmful agricultural and public health pests. Secondary... -
Federal
Genomic structure of the gene for mouse germ cell nuclear factor (GCNF)
U.S. Department of Health & Human Services —
Background: The germ cell nuclear factor (GCNF, also known as retinoid acid receptor-related testis-associated receptor, neuronal cell nuclear receptor or NR6A1) is... -
Federal
Hamster oocyte membrane potential and ion permeability vary with preantral cumulus cell attachment and developmental stage
U.S. Department of Health & Human Services —
Background In vitro maturation of mammalian oocytes is an area of great interest due to its potential application in the treatment of infertility. The morphological... -
Federal
Transcriptional response of human mast cells stimulated via the FcεRI and identification of mast cells as a source of IL-11
U.S. Department of Health & Human Services —
Background In asthma and other allergic disorders, the activation of mast cells by IgE and antigen induces the cells to release histamine and other mediators of... -
Federal
Early bronchopulmonary involvement in Crohn disease: a case report
U.S. Department of Health & Human Services —
Background Bronchopulmonary manifestations of Crohn disease have been rarely described in children, including both subclinical pulmonary involvement and severe lung... -
Federal
Predictors of refusal to participate: a longitudinal health survey of the elderly in Australia
U.S. Department of Health & Human Services —
Background The loss of participants in longitudinal studies due to non-contact, refusal or death can introduce bias into the results of such studies. The study... -
Federal
Expression of c-
U.S. Department of Health & Human Services —
Background A study was undertaken to resolve preliminary conflicting results on the proliferation of leukemia cells observed with different c-myc antisense... -
Federal
Research Article: BMC Infectious Diseases
U.S. Department of Health & Human Services —
Background Pyrazinamide (PZA) is among the first-line drugs for the treatment of tuberculosis. In vitro, it kills semidormant mycobacteria only at low pH. The purpose... -
Federal
In silico discovery of novel Retinoic Acid Receptor agonist structures
U.S. Department of Health & Human Services —
Background Several Retinoic Acid Receptors (RAR) agonists have therapeutic activity against a variety of cancer types; however, unacceptable toxicity profiles have... -
Federal
Cloning and characterization of the rat homologues of the Inhibitor of Apoptosis protein 1, 2, and 3 genes.
U.S. Department of Health & Human Services —
Background Inhibitor of Apoptosis (IAP) proteins are key intrinsic regulators of apoptosis induced by a variety of triggers. We isolated the rat Inhibitor of... -
Federal
Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown
U.S. Department of Health & Human Services —
Background A family of aspartate-specific cysteinyl proteases, named caspases, mediates programmed cell death, apoptosis. In this function, caspases are important for... -
Federal
Introducing evidence based medicine to the journal club, using a structured pre and post test: a cohort study
U.S. Department of Health & Human Services —
Background Journal Club at a University-based residency program was restructured to introduce, reinforce and evaluate residents understanding of the concepts of...