2,009 datasets found
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Federal
Agonizing Hedgehog
U.S. Department of Health & Human Services —
It is a rare treat when a drug discovery program teaches us something about the biology of the process that it attempts to modulate. The paper by Maria Frank-... -
Federal
Critical Carenon-peer-review research depository
U.S. Department of Health & Human Services —
The tradition of circulating research findings before peerreview is old and continues today. In addition to the informal circulation of non-peer-reviewed research... -
Federal
T cells that are naturally tolerant to cartilage-derived type II collagen are involved in the development of collagen-induced arthritis
U.S. Department of Health & Human Services —
The immunodominant T-cell epitope that is involved in collagen-induced arthritis (CIA) is the glycosylated type II collagen (CII) peptide 256-270. In CII transgenic... -
Federal
Biochemical, electron microscopic and immunohistological observations of cationic detergent-extracted cells: detection and improved preservation of microextensions and ultramicroextensions
U.S. Department of Health & Human Services —
Background Filopodia, retraction fibers and microvilli, are fragile microextensions of the plasma membrane that are easily damaged by mechanical force during specimen... -
Federal
Conducting systematic reviews of diagnostic studies: didactic guidelines
U.S. Department of Health & Human Services —
Background Although guidelines for critical appraisal of diagnostic research and meta-analyses have already been published, these may be difficult to understand for... -
Federal
Intensive care transfers
U.S. Department of Health & Human Services —
The demand for intensive care has increased relentlessly over the past 30 years. It is now regarded as a necessity rather than a luxury. The provision of intensive... -
Federal
Small-scale analysis of exopolysaccharides from
U.S. Department of Health & Human Services —
Background Exopolysaccharides (EPSs) produced by lactic acid bacteria are important for the texture of fermented foods and have received a great deal of interest... -
Federal
Signal analysis of behavioral and molecular cycles
U.S. Department of Health & Human Services —
Background Circadian clocks are biological oscillators that regulate molecular, physiological, and behavioral rhythms in a wide variety of organisms. While behavioral... -
Federal
Experimental arthritis induced by a clinical
U.S. Department of Health & Human Services —
Background Mycoplasma fermentans has been associated with rheumatoid arthritis. Recently, it was detected in the joints and blood of patients with rheumatoid... -
Federal
Envelope structure of
U.S. Department of Health & Human Services —
Background Many bacteria swim by rotating helical flagellar filaments [1]. Waterbury et al. [15] discovered an exception, strains of the cyanobacterium Synechococcus... -
Federal
Long-term vitamin E supplementation fails to reduce lipid peroxidation in people at cardiovascular risk: analysis of underlying factors
U.S. Department of Health & Human Services —
Background Antioxidant supplementation with vitamin E had no effect in the prevention of cardiovascular diseases (CVD) in three recent large, randomized clinical... -
Federal
Research Article: BMC Medical Genetics
U.S. Department of Health & Human Services —
Background SFHR (small fragment homologous replacement)-mediated targeting is a process that has been used to correct specific mutations in mammalian cells. This... -
Federal
Tumor necrosis factor and lymphotoxin-alpha genetic polymorphisms and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study of patients treated with BFM therapy
U.S. Department of Health & Human Services —
Background Circulating levels of tumor necrosis factor (TNF) and lymphotoxin-α (LT-α) have been associated with outcome in solid and hematologic malignancies. Within... -
Federal
Antigen-specific cytometry
U.S. Department of Health & Human Services —
From its origins in the 16thcentury, microscopy has allowed the cell, as the basic unit of eukaryotic life and disease, to be identified and analyzed. Today,... -
Federal
Blood substitutes
U.S. Department of Health & Human Services —
Blood substitutes have long been sought after, and artificial oxygen carriers may soon become a reality. Despite increased safety of allogeneic blood in terms of... -
Federal
Mutation analysis of the CHK2 gene in breast carcinoma and other cancers
U.S. Department of Health & Human Services —
Background Mutations in the CHK2 gene at chromosome 22q12.1 have been reported in families with Li-Fraumeni syndrome. Chk2 is an effector kinase that is activated in... -
Federal
Transcriptional programs activated by exposure of human prostate cancer cells to androgen
U.S. Department of Health & Human Services —
DNA microarrays were used to examine the temporal program of gene expression following treatment of a human prostate cancer cell line with androgen. Significant... -
Federal
Interconversion ofAnthozoaGFP-like fluorescent and non-fluorescent proteins by mutagenesis
U.S. Department of Health & Human Services —
Within the family of green fluorescent protein (GFP) homologs, one can mark two main groups, specifically, fluorescent proteins (FPs) and non-fluorescent or... -
Federal
International variation in ethics committee requirements: comparisons across five Westernised nations
U.S. Department of Health & Human Services —
Background Ethics committees typically apply the common principles of autonomy, nonmaleficence, beneficence and justice to research proposals but with variable... -
Federal
The measurement of lung water
U.S. Department of Health & Human Services —
Introduction: In this review, we compare the spectrum of currently available methods for quantifying pulmonary edema in patients. Review: Imaging and indicator...
2,009 datasets found