2,009 datasets found
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Federal
Mesenchymally-derived Insulin-like growth factor 1 provides a paracrine stimulus for trophoblast migration
U.S. Department of Health & Human Services —
Background Trophoblast migration into maternal decidua is essential for normal pregnancy. It occurs in a defined time window, is spatially highly restricted, and is... -
Federal
Quantitation of the distribution and flux of myosin-II during cytokinesis
U.S. Department of Health & Human Services —
Background During cytokinesis, the cell's equator contracts against the cell's global stiffness. Identifying the biochemical basis for these mechanical parameters is... -
Federal
mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships
U.S. Department of Health & Human Services —
The 5'-terminal cap structure plays an important role in many aspects of mRNA metabolism. Capping enzymes encoded by viruses and pathogenic fungi are attractive... -
Federal
Mining microarray expression data by literature profiling
U.S. Department of Health & Human Services —
The lack of efficient techniques for assessing the biological implications of microarray gene-expression data remains an important obstacle in exploiting this... -
Federal
Functional associations of proteins in entire genomes by means of exhaustive detection of gene fusions
U.S. Department of Health & Human Services —
Background It has recently been shown that the detection of gene fusion events across genomes can be used for predicting functional associations of proteins,... -
Federal
Different effects of rat interferon alpha, beta and gamma on rat hepatic stellate cell proliferation and activation
U.S. Department of Health & Human Services —
Background Liver fibrosis is the common sequel of chronic liver diseases. Recent studies have identified hepatic stellate cells as the primary cell type mediating... -
Federal
Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in
U.S. Department of Health & Human Services —
RNAi can be achieved by feeding worms Escherichia coli expressing dousble-stranded RNA corresponding to a specific gene. An optimized feeding method is presented that... -
Federal
Platelet glycoprotein IIb/IIIa receptor blockade in coronary artery disease
U.S. Department of Health & Human Services —
Glycoprotein IIb/IIIa inhibitors represent a new promising class of antiplatelet medications. Their use in acute coronary syndromes and for patients undergoing... -
Federal
Imaging of Dynamic Changes of the Actin Cytoskeleton in Microextensions of Live NIH3T3 Cells with a GFP Fusion of the F-Actin Binding Domain of Moesin
U.S. Department of Health & Human Services —
Background The cell surface undergoes continuous change during cell movement. This is characterized by transient protrusion and partial or complete retraction of... -
Federal
Serine / threonine protein phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling
U.S. Department of Health & Human Services —
Background In most cells glucocorticoid receptors (GR) reside predominately in the cytoplasm. Upon hormone binding, the GR translocates into the nucleus, where the... -
Federal
Assessing the heritability of attentional networks
U.S. Department of Health & Human Services —
Background Current efforts to study the genetics of higher functions have been lacking appropriate phenotypes to describe cognition. One of the problems is that many... -
Federal
The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells
U.S. Department of Health & Human Services —
Background The cyclin-dependent kinase inhibitor p27 is a putative tumor suppressor that is downregulated in the majority of human prostate cancers. The mechanism of... -
Federal
Structural, functional, and evolutionary analysis of
U.S. Department of Health & Human Services —
Background Pyridine-2,6-bis(thiocarboxylic acid) (pdtc) is a small secreted metabolite that has a high affinity for transition metals, increases iron uptake... -
Federal
The inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in fibroblasts from patients with systemic sclerosis
U.S. Department of Health & Human Services —
The main manifestation of systemic sclerosis (SSc) is the overproduction of extracellular matrix, predominantly type I collagen. This study was undertaken to evaluate... -
Federal
Microarray profile of differentially expressed genes in a monkey model of allergic asthma
U.S. Department of Health & Human Services —
Background Inhalation of Ascaris suum antigen by allergic monkeys causes an immediate bronchoconstriction and delayed allergic reaction, including a pulmonary... -
Federal
Use of the direct puncture technique in management of capillaro-venous malformations: case report
U.S. Department of Health & Human Services —
Background Preoperative devascularization of the capillaro-venous malformations located in the aero-digestive tract is important for surgeons, to minimize blood loss... -
Federal
The genetic structure of recombinant inbred mice: high-resolution consensus maps for complex trait analysis
U.S. Department of Health & Human Services —
Background Recombinant inbred (RI) strains of mice are an important resource used to map and analyze complex traits. They have proved particularly effective in... -
Federal
Predictors of positive health in disability pensioners: a population-based questionnaire study using Positive Odds Ratio
U.S. Department of Health & Human Services —
Background Determinants of ill-health have been studied far more than determinants of good and improving health. Health promotion measures are important even among... -
Federal
The challenge of early synovitis: multiple pathways to a common clinical syndrome
U.S. Department of Health & Human Services —
The challenge of early synovitis: multiple pathways to a common clinical syndrome -
Federal
Mutant loxP vectors for selectable marker recycle and conditional knock-outs
U.S. Department of Health & Human Services —
Background Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40...
2,009 datasets found