2,009 datasets found
-
Federal
High correlation between the turnover of nucleotides under mutational pressure and the DNA composition
U.S. Department of Health & Human Services —
Background Any DNA sequence is a result of compromise between the selection and mutation pressures exerted on it during evolution. It is difficult to estimate the... -
Federal
Achieving sustainable quality in maternity services – using audit of incontinence and dyspareunia to identify shortfalls in meeting standards
U.S. Department of Health & Human Services —
Background Some complications of childbirth (for example, faecal incontinence) are a source of social embarrassment for women, and are often under reported.... -
Federal
Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line.
U.S. Department of Health & Human Services —
Background Aquaporin-1 (AQP1) channels are constitutively active water channels that allow rapid transmembrane osmotic water flux, and also serve as cyclic-GMP-gated... -
Federal
Optimisation of transgene action at the post-transcriptional level: high quality parthenocarpic fruits in industrial tomatoes
U.S. Department of Health & Human Services —
Background Genetic engineering of parthenocarpy confers to horticultural plants the ability to produce fruits under environmental conditions that curtail fruit... -
Federal
Pharmacological basis for the therapy of pain and inflammation with nonsteroidal anti-inflammatory drugs
U.S. Department of Health & Human Services —
Nonsteroidal anti-inflammatory drugs (NSAIDs) belong to the most frequently used drugs. The discovery of an inducible isoform of cyclo-oxygenase (COX-2) has led to an... -
Federal
The lung as a route for systemic delivery of therapeutic proteins and peptides
U.S. Department of Health & Human Services —
The large surface area, good vascularization, immense capacity for solute exchange and ultra-thinness of the alveolar epithelium are unique features of the lung that... -
Federal
Influence of twenty-five per cent human serum albumin on total and ionized calcium concentrations
U.S. Department of Health & Human Services —
Background: A inverse correlation has been found between changes in ionized calcium concentrations and the addition of albumin in vitro, which may explain adverse... -
Federal
A role for Seven in Absentia Homolog (Siah1a) in metabotropic glutamate receptor signaling
U.S. Department of Health & Human Services —
Background The mammalian homologue of Seven in Absentia (Siah) can act in the ubiquitin/proteasome pathway. Recent work has shown that Siah can bind group I... -
Federal
Weather conditions and sudden sensorineural hearing loss
U.S. Department of Health & Human Services —
Background Climatic or meteorological condition changes have been implicated in the pathogenesis of Idiopathic Sudden Sensorineural Hearing Loss (ISSHL). We... -
Federal
Modulation of intracellular calcium and proliferative activity of invertebrate and vertebrate cells by ethylene
U.S. Department of Health & Human Services —
Background Ethylene is a widely distributed alkene product which is formed enzymatically (e.g., in plants) or by photochemical reactions (e.g., in the upper oceanic... -
Federal
A human RNA polymerase II subunit is encoded by a recently generated multigene family
U.S. Department of Health & Human Services —
Background The sequences encoding the yeast RNA polymerase II (RPB) subunits are single copy genes. Results While those characterized so far for the human (h) RPB are... -
Federal
Thrombocytopenia in critically ill surgical patients: a case-control study evaluating attributable mortality and transfusion requirements
U.S. Department of Health & Human Services —
Background: That thrombocytopenia results in increased mortality or transfusion requirements has not been confirmed by previous studies. We performed a case-control... -
Federal
Carbon and nitrogen substrate utilization by archival
U.S. Department of Health & Human Services —
Background A collection of over 20,000 Salmonella typhimurium LT2 mutants, sealed for four decades in agar stabs, is a unique resource for study of genetic and... -
Federal
Hisactophilin is involved in osmoprotection in Dictyostelium
U.S. Department of Health & Human Services —
Background Dictyostelium cells exhibit an unusual stress response as they protect themselves against hyperosmotic stress. Cytoskeletal proteins are recruited from the... -
Federal
Locations of several novel 2'-
U.S. Department of Health & Human Services —
Background Ribose 2'-O-methylation, the most common nucleotide modification in mammalian rRNA, is directed by the C/D box small nucleolar RNAs (snoRNAs). Thus far,... -
Federal
Workers' compensation claims related to natural rubber latex gloves among Oregon healthcare employees from 1987–1998
U.S. Department of Health & Human Services —
Background Occupational reaction to natural rubber latex (NRL) glove use by healthcare employees has been an area of increasing concern. Unfortunately, there is... -
Federal
HIV infection and aging: enhanced Interferon- and Tumor Necrosis Factor-alpha production by the CD8
U.S. Department of Health & Human Services —
Background T cells from HIV+ and aged individuals show parallels in terms of suppressed proliferative activity and interleukin-2 (I1-2) production and an increased... -
Federal
Dopaminergic neurons in the brain and dopaminergic innervation of the albumen gland in mated and virgin helisoma duryi (mollusca: pulmonata)
U.S. Department of Health & Human Services —
Background Dopamine was shown to stimulate the perivitelline fluid secretion by the albumen gland. Even though the albumen gland has been shown to contain... -
Federal
Cisapride decreases gastric content aspiration in mechanically ventilated patients
U.S. Department of Health & Human Services —
Objective: To determine the effect of the prokinetic agent cisapride in the prevention of aspiration of gastric contents. Design: A prospective randomized two-period... -
Federal
Collaborative interactions between neutrophil elastase and metalloproteinases in extracellular matrix degradation in three-dimensional collagen gels
U.S. Department of Health & Human Services —
Background Extended culture of monocytes and fibroblasts in three-dimensional collagen gels leads to degradation of the gels (see linked study in this issue,...
2,009 datasets found