96 datasets found
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Federal
Plasticity of the human IgM repertoire in response to a long-term spaceflight
National Aeronautics and Space Administration —
Immune dysregulation is among the main adverse outcomes of spaceflight. Despite its crucial role in host protection effects on the human antibody repertoire are... -
Federal
During development the Sku5 mutant roots engage different genes than wild type WS roots either on the ground or in spaceflight.
National Aeronautics and Space Administration —
The wild type WS plants and the Sku5 mutant plants in the WS background were germinated on ISS or on the ground and the gene expression profiles in roots at 4 days or... -
Federal
Genes Required for Survival in Microgravity Revealed by Genome-Wide Yeast Deletion Collections Cultured during Spaceflight
National Aeronautics and Space Administration —
Spaceflight is a unique environment with profound effects on biological systems including tissue redistribution and musculoskeletal stresses. However the more subtle... -
Federal
RNA-Seq transcriptome analysis of reactive oxygen species gene network in Mizuna plants grown in long-term space flight
National Aeronautics and Space Administration —
Space environment is suspected to generate reactive oxygen species (ROS) and induce oxidative stress in plants however little is known about the gene expression of... -
Federal
miRNA signature detection and countermeasures against HZE radiation exposure for tissue degeneration-Liver tissue
National Aeronautics and Space Administration —
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA... -
Federal
Transcriptome analysis of murine spleen in space
National Aeronautics and Space Administration —
Our study aims to comprehensively understand effects induced by the space environment on mammals. To achieve this aim we analyze the male mice housed under... -
Federal
International Space Station - Microbial Observatory of Pathogenic Virus Bacteria and Fungi project
National Aeronautics and Space Administration —
This study investigated the interplay between the microbial community of the International Space Station and its crew. Environmental samples were collected from 8... -
Federal
A study of gene expression influenced by simulated microgravity in human lymphoblastoid cells
National Aeronautics and Space Administration —
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the... -
Federal
Rodent Research-1 (RR1) National Lab Validation Flight: Mouse liver transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Reasearch-1 National Lab (RR-1 CASIS) experiment was performed to study the effect of microgravity on muscle wasting. RNA DNA and protein were purified... -
Federal
Impact of spaceflight on gene expression in the thymus
National Aeronautics and Space Administration —
The thymus undergoes atrophy during spaceflight. In this study we analyzed gene expression of the thymus of mice on board International space station to elucidate... -
Federal
Whole Metagenome Profiles of Particulates Collected from the International Space Station
National Aeronautics and Space Administration —
The microbial composition of the International Space Station (ISS) environment is of critical interest due to potential impact of its constituents on human health and... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
RR-1 is a validation flight to evaluate the hardware operational and science capabilities of the Rodent Research Project on the ISS. RNA DNA and protein were purified... -
Federal
Comparative Transcriptomic Analysis of Adult Medaka Tissues Sampled after Adaptation to a Space Environment
National Aeronautics and Space Administration —
To understand how humans adapt to space environments many experiments can be conducted on astronauts while they work aboard the Space Shuttle or the International... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse kidney transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Medaka Osteoclast
National Aeronautics and Space Administration —
During space flight bone mineral density is decreased by the influence of osteoclast activation which molecular mechanism is expectantly investigated. In the study of... -
Federal
Comparative Transcriptomic Analysis of Adult Medaka Tissues Sampled after Adaptation to a Space Environment
National Aeronautics and Space Administration —
To understand how humans adapt to space environments many experiments can be conducted on astronauts while they work aboard the Space Shuttle or the International...
96 datasets found