2,009 datasets found
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Federal
Autoimmune response to U1 small nuclear ribonucleoprotein (U1 snRNP) associated with cytomegalovirus infection
U.S. Department of Health & Human Services —
The induction of autoantibodies to U1 small nuclear ribonucleoprotein (U1 snRNP) complexes is not well understood. We present evidence that healthy individuals with... -
Federal
A search for reverse transcriptase-coding sequences reveals new non-LTR retrotransposons in the genome of
U.S. Department of Health & Human Services —
Background: Non-long terminal repeat (non-LTR) retrotransposons are eukaryotic mobile genetic elements that transpose by reverse transcription of an RNA intermediate.... -
Federal
Setting of graded levels of a protein in yeast by a t-degron technique as applied to phosphoglycerate mutase
U.S. Department of Health & Human Services —
Background Setting of graded levels of a protein for in vivo studies by controlled gene expression has inconveniences, and we here explore the use of the t-degron... -
Federal
Malarone treatment failure and
U.S. Department of Health & Human Services —
We report the first in vitro and genetic confirmation of Malarone® (GlaxoSmithKline; atovaquone and proguanil hydrochloride) resistance in Plasmodium falciparum... -
Federal
Asymmetric interactions in the adenosine-binding pockets of the MS2 coat protein dimer
U.S. Department of Health & Human Services —
Background The X-ray structure of the MS2 coat protein-operator RNA complex reveals the existence of quasi-synmetric interactions of adenosines -4 and -10 in pockets... -
Federal
Genomic organization and single-nucleotide polymorphism map of desmuslin, a novel intermediate filament protein on chromosome 15q26.3
U.S. Department of Health & Human Services —
Background Desmuslin is an α-dystrobrevin-interacting protein expressed primarily in heart and skeletal muscle. The desmuslin protein interacts with and is closely... -
Federal
Decreased expression of the mannose 6- phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells
U.S. Department of Health & Human Services —
Background Loss or mutation of the mannose 6-phosphate/insulin-like growth factor-II receptor (M6P/IGF2R) has been found in breast cancer. However, whether or not... -
Federal
Screening for sequence-specific RNA-BPs by comprehensive UV crosslinking
U.S. Department of Health & Human Services —
Background Specific cis-elements and the associated trans-acting factors have been implicated in the post-transcriptional regulation of gene expression. In the era of... -
Federal
The promise of e-Health – a Canadian perspective
U.S. Department of Health & Human Services —
Canadians value their health care system above any other social program. Canada's system of health care faces significant financial and population pressures, relating... -
Federal
Transcriptional regulation of lung development: emergence of specificity
U.S. Department of Health & Human Services —
The lung is the product of a set of complex developmental interactions between two distinct tissues, the endodermally derived epithelium and the mesoderm. Each tissue... -
Federal
Phylogenetic analysis of methanogens from the bovine rumen
U.S. Department of Health & Human Services —
Background Interest in methanogens from ruminants has resulted from the role of methane in global warming and from the fact that cattle typically lose 6 % of ingested... -
Federal
Patient attitudes toward using computers to improve health services delivery
U.S. Department of Health & Human Services —
Background The aim of this study was to examine the acceptability of point of care computerized prompts to improve health services delivery among a sample of primary... -
Federal
From the cell biology to the development of new chemotherapeutic approaches against trypanosomatids: dreams and reality.
U.S. Department of Health & Human Services —
Members of the Trypanosomatidae family comprise a large number of species that are causative agents of important diseases such as sleeping sickness, Chagas' disease... -
Federal
Lactate: A key metabolite in the intercellular metabolic interplay
U.S. Department of Health & Human Services —
Most physicians involved in intensive care consider lactate solely as a deleterious metabolite, responsible for high morbidity and bad prognosis in severe patients.... -
Federal
Nitric oxide: a pro-inflammatory mediator in lung disease?
U.S. Department of Health & Human Services —
Inflammatory diseases of the respiratory tract are commonly associated with elevated production of nitric oxide (NO•) and increased indices of NO• -dependent... -
Federal
Cell-cell interactions in synovitis: Interactions between T lymphocytes and synovial cells
U.S. Department of Health & Human Services —
Mechanisms whereby T lymphocytes contribute to synovial inflammation in rheumatoid arthritis are poorly understood. Here we review data that indicate an important... -
Federal
Utility of the Mayo End-Stage Liver Disease (MELD) score in assessing prognosis of patients with alcoholic hepatitis
U.S. Department of Health & Human Services —
Background Alcoholic hepatitis is characterized by acute, or acute-on-chronic hepatic failure and associated with a high mortality. Specific therapies should be... -
Federal
Immune ablation and stem-cell therapy in autoimmune disease: Introduction
U.S. Department of Health & Human Services —
Immune ablation and stem-cell therapy in autoimmune disease: Introduction -
Federal
Stress responses and replication of plasmids in bacterial cells
U.S. Department of Health & Human Services —
Plasmids, DNA (or rarely RNA) molecules which replicate in cells autonomously (independently of chromosomes) as non-essential genetic elements, play important roles... -
Federal
Adhesion molecules in different treatments of acute myocardial infarction
U.S. Department of Health & Human Services —
Background: Tissue damage after ischemia and reperfusion involves leukocyte endothelial interactions mediated by cell adhesion molecules. This study was designed to...
2,009 datasets found