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Federal
Evidence for modulation of pericryptal sheath myofibroblasts in rat descending colon by Transforming Growth Factor β and Angiotensin II.
U.S. Department of Health & Human Services —
Background Absorption of water and Na+ in descending colonic crypts is dependent on the barrier function of the surrounding myofibroblastic pericryptal sheath. Here... -
Federal
Search for intracranial aneurysm susceptibility gene(s) using Finnish families
U.S. Department of Health & Human Services —
Background Cerebrovascular disease is the third leading cause of death in the United States, and about one-fourth of cerebrovascular deaths are attributed to ruptured... -
Federal
Abdominal compartment syndrome: does intra-cystic pressure reflect actual intra-abdominal pressure? A prospective study in surgical patients
U.S. Department of Health & Human Services —
Background: Abdominal compartment syndrome is defined as the adverse physiologic effects of increased intra-abdominal pressure. Prolonged, unrelieved pressure may... -
Federal
Circulating cytotoxic CD8
U.S. Department of Health & Human Services —
Circulating CD8+ CD28- T cells were found to be expanded more in patients with ankylosing spondylitis than in an age-matched healthy population (41.2 ± 17.7% versus... -
Federal
Increased expression of ICAM-1, VCAM-1, MCP-1, and MIP-1α by spinal perivascular macrophages during experimental allergic encephalomyelitis in rats
U.S. Department of Health & Human Services —
Background T-cells extravasation and CNS parenchyma infiltration during autoimmune neurodegenerative disease can be evoked by local antigen presenting cells. Studying... -
Federal
Leukocyte adhesion and recruitment, and alpha-1-antitrypsin deficiency: a report from ATS 2001, May 18-23, San Francisco
U.S. Department of Health & Human Services —
The program at this year's American Thoracic Society international conference included over 300 scientific and clinical symposia. In this report I have reviewed the... -
Federal
Control of dinucleoside polyphosphates by the
U.S. Department of Health & Human Services —
Background The FHIT gene is lost early in the development of many tumors. Fhit possesses intrinsic ApppA hydrolase activity though ApppA cleavage is not required for... -
Federal
Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol
U.S. Department of Health & Human Services —
Background Suspected acute appendicitis is the most frequent cause for emergency operations in visceral surgery worldwide. In approximately twenty percent of all... -
Federal
The probability of cost-effectiveness
U.S. Department of Health & Human Services —
Background The study of cost-effectiveness comparisons between competing medical interventions has led to a variety of proposals for quantifying cost-effectiveness.... -
Federal
Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)
U.S. Department of Health & Human Services —
Background Although much is known about the regulation of osteoclast (OC) formation and activity, little is known about OC senescence. In particular, the fate of of... -
Federal
Variations in chemoprophylaxis for meningococcal disease: a retrospective case note review, analysis of routine prescribing data and questionnaire of general practitioners
U.S. Department of Health & Human Services —
Background Invasive meningococcal disease is a significant cause of mortality and morbidity in the UK. Administration of chemoprophylaxis to close contacts reduces... -
Federal
Apolipoprotein C3 SstI polymorphism and triglyceride levels in Asian Indians
U.S. Department of Health & Human Services —
Background A close association between Sst I polymorphism in the 3' untranslated region of the apolipoproteinC3 (APOC3) gene and levels of plasma triglycerides (TG)... -
Federal
The major transcription initiation site of the
U.S. Department of Health & Human Services —
Background The cyclin-dependent kinase inhibitor p27Kip1 is essential for proper control of cell cycle progression. The levels of p27Kip1 are regulated by several... -
Federal
An essential guide to the literature
U.S. Department of Health & Human Services —
An essential guide to the literature -
Federal
Survey of human mitochondrial diseases using new genomic/proteomic tools
U.S. Department of Health & Human Services —
Background We have constructed Bayesian prior-based, amino-acid sequence profiles for the complete yeast mitochondrial proteome and used them to develop methods for... -
Federal
Synthesis of a novel hepatitis C virus protein by ribosomal frameshift
U.S. Department of Health & Human Services —
Hepatitis C virus (HCV) is an important human pathogen that affects ∼100 million people worldwide. Its RNA genome codes for a polyprotein, which is cleaved by viral... -
Federal
The vasculature and its role in the damaged and healing tendon
U.S. Department of Health & Human Services —
Tendon pathology has many manifestations, from spontaneous rupture to chronic tendinitis or tendinosis; the etiology and pathology of each are very different, and... -
Federal
The International Sepsis Forum's controversies in sepsis: corticosteroids should not be routinely used to treat septic shock
U.S. Department of Health & Human Services —
Corticosteroid treatment of severe sepsis has been one of the most controversial clinical issues in critical care. In fact, few agents can claim to have been... -
Federal
Delta Opioid activation of the Mitogen-activated protein kinase cascade does not require transphosphorylation of Receptor Tyrosine Kinases
U.S. Department of Health & Human Services —
Background In this study, we investigated the mechanism(s) by which delta opioids induce their potent activation of extracellular signal-regulated protein kinases... -
Federal
How long should angiotensin-converting enzyme inhibitors be given to patients following myocardial infarction: implications of the HOPE trial
U.S. Department of Health & Human Services —
Long-term treatment with angiotensin-converting enzyme inhibitors reduces post-infarction morbidity and mortality in patients with left ventricular (LV) systolic...