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Federal
Blood substitutes: Haemoglobin therapeutics in clinical practice
U.S. Department of Health & Human Services —
Early approaches to the development of oxygen carriers involved the use of stroma-free hemoglobin solutions. These solutions did not require blood typing or... -
Federal
Evidence for large domains of similarly expressed genes in the
U.S. Department of Health & Human Services —
Background Transcriptional regulation in eukaryotes generally operates at the level of individual genes. Regulation of sets of adjacent genes by mechanisms operating... -
Federal
T Wave Alternans in high arrhythmic risk patients: Analysis in time and frequency domains: A pilot study
U.S. Department of Health & Human Services —
Background T wave alternans (TA) is a repolarisation phenomenon manifesting as a microvolt beat to beat change in the amplitude of the T wave and ST segment. TA has... -
Federal
Erythropoietin, uncertainty principle and cancer related anaemia
U.S. Department of Health & Human Services —
Background This study was designed to evaluate if erythropoietin (EPO) is effective in the treatment of cancer related anemia, and if its effect remains unchanged... -
Federal
Thyroxine signal transduction in liver cells involves phospholipase C and phospholipase D activation. Genomic independent action of thyroid hormone
U.S. Department of Health & Human Services —
Background Numerous investigations demonstrate a novel role of thyroid hormone as a modulator of signal transduction. Protein kinase C (PKC) is critical to the... -
Federal
The regulation of CD5 expression in murine T cells
U.S. Department of Health & Human Services —
Background CD5 is a pan-T cell surface marker that is also present on a subset of B cells, B-1a cells.Functional and developmental subsets of T cells express... -
Federal
Peptide binding characteristics of the non-classical class Ib MHC molecule HLA-E assessed by a recombinant random peptide approach
U.S. Department of Health & Human Services —
Background Increasing evidence suggests that the effect of HLA-E on Natural Killer (NK) cell activity can be affected by the nature of the peptides bound to this non-... -
Federal
The emerging periplasm-localized subclass of AroQ chorismate mutases, exemplified by those from
U.S. Department of Health & Human Services —
Background Chorismate mutases of the AroQ homology class are widespread in the Bacteria and the Archaea. Many of these exist as domains that are fused with other... -
Federal
Using single nucleotide polymorphisms as a means to understanding the pathophysiology of asthma
U.S. Department of Health & Human Services —
Asthma is the most common chronic childhood disease in the developed nations, and is a complex disease that has high social and economic costs. Studies of the genetic... -
Federal
B cells in rheumatoid arthritis
U.S. Department of Health & Human Services —
Normally the immune response is restricted to the peripheral secondary lymphoid organs. However, additional ectopic lymphoid tissue may develop at chronic sites of... -
Federal
Sex steroids do not affect shigatoxin cytotoxicity on human renal tubular or glomerular cells
U.S. Department of Health & Human Services —
Background The greater susceptibility of children to renal injury in post-diarrheal hemolytic-uremic syndrome (HUS) may be related, at least in part, to heightened... -
Federal
Interaction of neuronal nitric oxide synthase with alpha
U.S. Department of Health & Human Services —
Background The C-terminal four amino acids (GEEV) of human α1A-adrenergic receptors (ARs) have been reported to interact with the PDZ domain of neuronal nitric oxide... -
Federal
Interaction of the Yersinia pestis type III regulatory proteins LcrG and LcrV occurs at a hydrophobic interface: correction
U.S. Department of Health & Human Services —
Interaction of the Yersinia pestis type III regulatory proteins LcrG and LcrV occurs at a hydrophobic interface: correction -
Federal
Experience with prolonged induced hypothermia in severe head injury
U.S. Department of Health & Human Services —
Background: Recent prospective controlled trials of induced moderate hypothermia (32⌓34°C) for relatively short periods (24⌓48 h) in patients with severe head injury... -
Federal
Monoclonal antibodies against the iron regulated outer membrane Proteins of
U.S. Department of Health & Human Services —
Background Iron is an important nutrient required by all forms of life.In the case of human hosts,the free iron availability is 10-18M,which is far less than what is... -
Federal
SNP frequency, haplotype structure and linkage disequilibrium in elite maize inbred lines
U.S. Department of Health & Human Services —
Background Recent studies of ancestral maize populations indicate that linkage disequilibrium tends to dissipate rapidly, sometimes within 100 bp. We set out to... -
Federal
Delta-Notch signaling and lateral inhibition in zebrafish spinal cord development: Correction
U.S. Department of Health & Human Services —
Delta-Notch signaling and lateral inhibition in zebrafish spinal cord development: Correction -
Federal
The effects of IgM-enriched immunoglobulin preparations in patients with severe sepsis [ISRCTN28863830]
U.S. Department of Health & Human Services —
Introduction In this prospective, randomized controlled study, we aimed to evaluate the effect of IgM-enriched immunoglobulin treatment on progression of organ... -
Federal
Ninth Asia Pacific League Of Associations For Rheumatology (APLAR) Congress, Beijing, China, 21-26 May, 2000
U.S. Department of Health & Human Services —
The Congress covered the broad field of rheumatology, with participants from China, the Asia Pacific League of Associations for Rheumatology (APLAR) region and the... -
Federal
Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue
U.S. Department of Health & Human Services —
Angiopoietins (Ang) are vascular endothelial cell-specific growth factors that play important roles principally during the later stages of angiogenesis. We have...