2,009 datasets found
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Federal
A possible cause of joint destruction in septic arthritis
U.S. Department of Health & Human Services —
A possible cause of joint destruction in septic arthritis -
Federal
The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p
U.S. Department of Health & Human Services —
Background The function of the fission yeast cullins Pcu1p and Pcu4p requires modification by the ubiquitin-related peptide Ned8p. A recent report by Lyapina et al.... -
Federal
Long term adaptation of a microbial population to a permanent metabolic constraint: overcoming thymineless death by experimental evolution of
U.S. Department of Health & Human Services —
Background To maintain populations of microbial cells under controlled conditions of growth and environment for an indefinite duration is a prerequisite for... -
Federal
Mutational analysis of Peroxiredoxin IV: exclusion of a positional candidate for multinodular goitre
U.S. Department of Health & Human Services —
Background Multinodular goitre (MNG) is a common disorder characterised by an enlargement of the thyroid, occurring as a compensatory response to hormonogenesis... -
Federal
Effect of alpha-tocopherol on pulmonary antioxidant defence system and lipid peroxidation in cigarette smoke inhaling mice
U.S. Department of Health & Human Services —
Background Free radicals generated in biological systems by cigarette smoke (CS) inhalation can cause oxidative stress in tissues, resulting in lipid peroxidation... -
Federal
Th2 cytokines and asthma: an introduction
U.S. Department of Health & Human Services —
Th2 cytokines and asthma: an introduction -
Federal
Antitubercular therapy decreases nitric oxide production in HIV/TB coinfected patients
U.S. Department of Health & Human Services —
Background Nitric oxide (NO) production is increased among patients with human immunodeficiency virus (HIV) infection and also among those with tuberculosis (TB). In... -
Federal
The Distributed Annotation System
U.S. Department of Health & Human Services —
Background Currently, most genome annotation is curated by centralized groups with limited resources. Efforts to share annotations transparently among multiple groups... -
Federal
Bone loss: Therapeutic approaches for preventing bone loss in inflammatory arthritis
U.S. Department of Health & Human Services —
Inflammatory arthritides are commonly characterized by localized and generalized bone loss. Localized bone loss in the form of joint erosions and periarticular... -
Federal
Identification ofSchistosoma mansonigender-associated gene transcripts by cDNA microarray profiling
U.S. Department of Health & Human Services —
Parasitic helminths of the genusSchistosomamate, achieve sexual maturity and produce eggs in the bloodstream of their definitive hosts, and the most important... -
Federal
Debate: Albumin administration should not be avoided
U.S. Department of Health & Human Services —
The recent Cochrane report on albumin administration is analysed and criticised on the grounds of clinical methodology, content and interpretation. Although it is... -
Federal
ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins
U.S. Department of Health & Human Services —
Background Annotations of completely sequenced genomes reveal that nearly half of the genes identified are of unknown function, and that some belong to... -
Federal
Isolation and characterization of new
U.S. Department of Health & Human Services —
Background Nuclear pore complexes (NPCs) are essential for facilitated, directional nuclear transport; however, the mechanism by which ~30 different nucleoporins... -
Federal
Design and intermediate results of the Lower Extremity Arterial Disease Event Reduction (LEADER)* trial of bezafibrate in men with lower extremity arterial disease [ISRCTN41194621]
U.S. Department of Health & Human Services —
Background Raised levels of both triglycerides and fibrinogen, each of which are reduced by bezafibrate, may contribute to lower extremity arterial disease (LEAD).... -
Federal
Phylogenetic relationships between
U.S. Department of Health & Human Services —
Background Phylogenetic relationships of the genus Hapalemur remains controversial, particularly within the Hapalemur griseus species group. In order to obtain more... -
Federal
The immunological effects of continuous veno-venous haemodiafiltration in critically ill patients
U.S. Department of Health & Human Services —
Background: Haemodynamic instability is common in septic patients with acute renal failure. Continuous veno-venous haemodiafiltration (CVVHD) is therefore used as an... -
Federal
Editorial comment
U.S. Department of Health & Human Services —
In this issue of the journal, Steinwaldet al[1] extend limited clinical studies and report an animal experiment showing that calcitonin precursors (predominantly... -
Federal
The Novartis-ILAR Rheumatology Prize 2001 Osteoarthritis: from molecule to man
U.S. Department of Health & Human Services —
During our careers, we have developed new and innovative concepts pertaining to the pathophysiology of osteoarthritis which have assisted in the development of new... -
Federal
Using heart-lung interactions to assess fluid responsiveness during mechanical ventilation
U.S. Department of Health & Human Services —
According to the Frank-Starling relationship, a patient is a 'responder' to volume expansion only if both ventricles are preload dependent. Mechanical ventilation... -
Federal
ICU Cornestone: A lecture that changed my practice
U.S. Department of Health & Human Services —
In 1982, the author attended a lecture by Professor Joseph Civetta dealing with the concept that, at times, the goal of care should be comfort rather than cure, and...
2,009 datasets found