2,009 datasets found
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Federal
Different conformations of nascent polypeptides during translocation across the ER membrane
U.S. Department of Health & Human Services —
Background In eukaryotic cells, proteins are translocated across the ER membrane through a continuous ribosome-translocon channel. It is unclear to what extent... -
Federal
A database for the provisional identification of species using only genotypes: web-based genome profiling
U.S. Department of Health & Human Services —
Background For a long time one could not imagine being able to identify species on the basis of genotype only as there were no technological means to do so. But... -
Federal
Nucleolar localization of an isoform of the IGF-I precursor
U.S. Department of Health & Human Services —
Background Alternative exons encode different isoforms of the human insulin-like growth factor-I (IGF-I) precursor without altering mature IGF-I. We hypothesized that... -
Federal
Early peri-operative hyperglycaemia and renal allograft rejection in patients
U.S. Department of Health & Human Services —
Background Patients with diabetes have an increased risk for allograft rejection, possibly related to peri-operative hyperglycaemia. Hyperglycaemia is also common... -
Federal
A glutamine-amidotransferase-like protein modulates FixT anti-kinase activity in
U.S. Department of Health & Human Services —
Background Nitrogen fixation gene expression in Sinorhizobium meliloti, the alfalfa symbiont, depends on a cascade of regulation that involves both positive and... -
Federal
Genetic snapshots of the
U.S. Department of Health & Human Services —
Background: In nitrate-poor soils, many leguminous plants form nitrogen-fixing symbioses with members of the bacterial family Rhizobiaceae. We selected Rhizobium sp.... -
Federal
The SWIRM domain: a conserved module found in chromosomal proteins points to novel chromatin-modifying activities
U.S. Department of Health & Human Services —
Using computational sequence-profile analysis methods, a previously uncharacterized, predicted α-helical domain of about 85 residues was identified in chromosomal... -
Federal
On the probability of cost-effectiveness using data from randomized clinical trials
U.S. Department of Health & Human Services —
Background Acceptability curves have been proposed for quantifying the probability that a treatment under investigation in a clinical trial is cost-effective. Various... -
Federal
Peroxynitrite decomposition catalyst prevents apoptotic cell death in a human astrocytoma cell line incubated with supernatants of HIV-infected macrophages
U.S. Department of Health & Human Services —
Background Oxidative stress has shown to contribute in the mechanisms underlying apoptotic cell death occuring in AIDS-dementia complex. Here we investigated the role... -
Federal
Experience with prolonged induced hypothermia in severe head injury
U.S. Department of Health & Human Services —
Experience with prolonged induced hypothermia in severe head injury -
Federal
Conservation and diversity of gene families explored using the CODEHOP strategy in higher plants
U.S. Department of Health & Human Services —
Background Availability of genomewide information on an increasing but still limited number of plants offers the possibility of identifying orthologues, or related... -
Federal
Sub-inhibitory concentrations of vancomycin prevent quinolone-resistance in a penicillin-resistant isolate of Streptococcus pneumoniae
U.S. Department of Health & Human Services —
Background The continuous spread of penicillin-resistant pneumococci represents a permanent threat in the treatment of pneumococcal infections, especially when... -
Federal
Inhaled nitric oxide reverses cell-free hemoglobin-induced pulmonary hypertension and decreased lung compliance. Preliminary results
U.S. Department of Health & Human Services —
Background: In order to test the hypothesis that inhaled nitric oxide (NO) reverses the pulmonary hypertension induced by αα-diaspirin crosslinked hemoglobin (ααHb),... -
Federal
A follow-up to "Anti-cytokine therapy in chronic destructive arthritis" by Wim B van den Berg
U.S. Department of Health & Human Services —
In recent years, the effectiveness of anti-TNF therapy in treating rheumatoid arthritis (RA) has become apparent. While trials of IL-1 receptor antagonist in RA have... -
Federal
Physical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays
U.S. Department of Health & Human Services —
Background Somatic cell mutants can be informative in the analysis of a wide variety of cellular processes. The use of map-based positional cloning strategies in... -
Federal
Activation of macrophages by silicones: phenotype and production of oxidant metabolites
U.S. Department of Health & Human Services —
Background The effect of silicones on the immune function is not fully characterized. In clinical and experimental studies, immune alterations associated with... -
Federal
Increasing the satisfaction of general practitioners with continuing medical education programs: A method for quality improvement through increasing teacher-learner interaction
U.S. Department of Health & Human Services —
Background Continuing medical education (CME) for general practitioners relies on specialist-based teaching methods in many settings. Formal lectures by specialists... -
Federal
Bouveret's syndrome complicated by distal gallstone ileus after laser lithotropsy using Holmium: YAG laser
U.S. Department of Health & Human Services —
Background Bouveret's syndrome is an unusual presentation of duodenal obstruction caused by the passage of a large gallstone through a cholecystoduodenal fistula.... -
Federal
Electrolytic ablation of the rat pancreas: a feasibility trial
U.S. Department of Health & Human Services —
Background Pancreatic cancer is a biologically aggressive disease with less than 20% of patients suitable for a "curative" surgical resection. This, combined with the... -
Federal
Mosaic chromosomal aberrations in synovial fibroblasts of patients with rheumatoid arthritis, osteoarthritis, and other inflammatory joint diseases
U.S. Department of Health & Human Services —
Chromosomal aberrations were comparatively assessed in nuclei extracted from synovial tissue, primary-culture (P-0) synovial cells, and early-passage synovial...
2,009 datasets found