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Federal
A prospective, cross-sectional study of anaemia and peripheral iron status in antiretroviral naïve, HIV-1 infected children in Cape Town, South Africa
U.S. Department of Health & Human Services —
Background Anaemia is a common manifestation of paediatric HIV infection. Although there are many causes, anaemia of chronic diseases is the most frequent type. In... -
Federal
Assessing the quality of reports of systematic reviews in pediatric complementary and alternative medicine
U.S. Department of Health & Human Services —
Objective To examine the quality of reports of complementary and alternative medicine (CAM) systematic reviews in the pediatric population. We also examined whether... -
Federal
Poly purine.pyrimidine sequences upstream of the beta-galactosidase gene affect gene expression in
U.S. Department of Health & Human Services —
Background Poly purine.pyrimidine sequences have the potential to adopt intramolecular triplex structures and are overrepresented upstream of genes in eukaryotes.... -
Federal
A C-terminal hydrophobic region is required for homo-oligomerization of the hepatitis E virus capsid (ORF2) protein
U.S. Department of Health & Human Services —
Hepatitis E virus (HEV) is the causative agent of hepatitis E, an acute form of viral hepatitis. The open reading frame 2 (ORF2) of HEV encodes the viral capsid... -
Federal
Aminoadipate reductase gene: a new fungal-specific gene for comparative evolutionary analyses
U.S. Department of Health & Human Services —
Background In fungi, aminoadipate reductase converts 2-aminoadipate to 2-aminoadipate 6-semialdehyde. However, other organisms have no homologue to the aminoadipate... -
Federal
Are the Cochrane group registers comprehensive? A case study of Japanese psychiatry trials
U.S. Department of Health & Human Services —
Background Language bias is a form of publication bias and constitutes a serious threat to meta-analyses. The Cochrane Controlled Trials Register is one attempt to... -
Federal
Low-volume jet injection for intradermal immunization in rabbits
U.S. Department of Health & Human Services —
Background This study tested a low-volume (20–30 μl/20–30 μg DNA) jet injection method for intradermal delivery of a DNA vaccine. Jet injection offers the advantages... -
Federal
Probing the importance and potential roles of the binding of the PH-domain protein Boi1 to acidic phospholipids
U.S. Department of Health & Human Services —
Background The related proteins Boi1 and Boi2, which appear to promote polarized growth in S. cerevisiae, both contain a PH (pleckstrin homology) and an SH3 (src... -
Federal
Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder
U.S. Department of Health & Human Services —
Background Alterations in arginine vasopressin regulation and secretion have been proposed as one possible biochemical abnormality in patients with obsessive-... -
Federal
Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals
U.S. Department of Health & Human Services —
Background Expression profiling holds great promise for rapid host genome functional analysis. It is plausible that host expression profiling in an infection could... -
Federal
Dynamic expression of a glutamate decarboxylase gene in multiple non-neural tissues during mouse development
U.S. Department of Health & Human Services —
Background Glutamate decarboxylase (GAD) is the biosynthetic enzyme for the neurotransmitter γ-aminobutyric acid (GABA). Mouse embryos lacking the 67-kDa isoform of... -
Federal
Exploring the conditional coregulation of yeast gene expression through fuzzy k-means clustering
U.S. Department of Health & Human Services —
A heuristically modified version of fuzzy k-means clustering has been used to identify overlapping clusters of yeast genes based on published gene-expression data... -
Federal
A prospective study of tracheopulmonary complications associated with the placement of narrow-bore enteral feeding tubes
U.S. Department of Health & Human Services —
Background: In order to determine the type and incidence of pulmonary complications associated with the placement of narrow-bore enteral feeding tubes we conducted a... -
Federal
Identification of stem cell units in the terminal end bud and duct of the mouse mammary gland
U.S. Department of Health & Human Services —
The mouse mammary gland may undergo cycles of proliferation, terminal differentiation, tissue remodeling, and more importantly malignant transformation. Mammary... -
Federal
Genotyping in the MHC locus: potential for defining predictive markers in sarcoidosis
U.S. Department of Health & Human Services —
In sarcoidosis, host genetic factors are discussed as contributing to disease susceptibility and course. Since tumor necrosis factor (TNF)-α is a central mediator of... -
Federal
Continuous haemofiltration in the intensive care unit
U.S. Department of Health & Human Services —
Continuous renal replacement therapy (CRRT) was first described in 1977 for the treatment of diuretic-unresponsive fluid overload in the intensive care unit (ICU).... -
Federal
Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease
U.S. Department of Health & Human Services —
There is mounting evidence for a role of the growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF) in inflammatory disease, including arthritis. In... -
Federal
Phenotyping ofCampylobacter jejuniandCampylobacter coliby a quantitative antibiogram [MIC] typing scheme using Euclidean distances [QATED]
U.S. Department of Health & Human Services —
EnteropathogenicCampylobacter jejuniandC. coliare presently the most common cause of acute bacterial gastroenteritis in the developed world. An understanding of... -
Federal
A geometric and algebraic view of MHC-peptide complexes and their binding properties
U.S. Department of Health & Human Services —
Background Major histocompatibility complex (MHC) molecules present peptides to T lymphocytes. It is of critical biological and medical importance to elucidate how... -
Federal
Investigating the mechanism of acoustically activated uptake of drugs from Pluronic micelles
U.S. Department of Health & Human Services —
Background This paper examines the mechanism of ultrasonic enhanced drug delivery from Pluronic micelles. In previous publications by our group, fluorescently labeled...