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Federal
Antibiotics for coughing in general practice: a questionnaire study to quantify and condense the reasons for prescribing
U.S. Department of Health & Human Services —
Background Antibiotics are being overprescribed in ambulant care, especially for respiratory tract infections (RTIs). Gaining insight into the actual reasons for... -
Federal
Antenatal infection/inflammation and postnatal lung maturation and injury
U.S. Department of Health & Human Services —
Chorioamnionitis is frequently associated with preterm deliveries before 30 weeks gestation. Chorioamnionitis correlates both with an increased risk of... -
Federal
Discordance between physical symptoms versus perception of severity by women with nausea and vomiting in pregnancy (NVP)
U.S. Department of Health & Human Services —
Background Nausea and vomiting in pregnancy (NVP) is a multifaceted condition that affects more than half of pregnant women and can range in severity from mild nausea... -
Federal
The role of collagenase in emphysema
U.S. Department of Health & Human Services —
The extracellular matrix is essential for the integrity of the lung and when disrupted can lead to the architectural changes seen in emphysema. The etiology of... -
Federal
Identification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5R
U.S. Department of Health & Human Services —
Background Vaccinia virus gene B1R encodes a serine/threonine protein kinase. In vitro this protein kinase phosphorylates ribosomal proteins Sa and S2 and vaccinia... -
Federal
Characterisation of silent and active genes for a variable large protein of
U.S. Department of Health & Human Services —
Background We report the characterisation of the variable large protein (vlp) gene expressed by clinical isolate A1 of Borrelia recurrentis; the agent of the life-... -
Federal
B lymphocytopenia in rheumatoid arthritis is associated with the DRB1 shared epitope and increased acute phase response
U.S. Department of Health & Human Services —
The influence of HLA DRB1 alleles on B-cell homeostasis was analyzed in 164 patients with rheumatoid arthritis (RA). The percentages of CD19+ B lymphocytes determined... -
Federal
Leptin in septic arthritis: decreased levels during infection and amelioration of disease activity upon its administration
U.S. Department of Health & Human Services —
Weight loss is typically found during severe infections, e.g. septic arthritis. The aim of our study was to evaluate the role of leptin, regulator of food intake and... -
Federal
MtnK, methylthioribose kinase, is a starvation-induced protein in Bacillus subtilis
U.S. Department of Health & Human Services —
Background Methylthioadenosine, the main by-product of spermidine synthesis, is degraded in Bacillus subtilis as adenine and methylthioribose. The latter is an... -
Federal
PRESTA: associating promoter sequences with information on gene expression
U.S. Department of Health & Human Services —
The software tool PRESTA (PRomoter EST Association) is designed for efficient recovery of characterized and partially verified promoters from GenBank and EMBL... -
Federal
Roughing up Smoothened: chemical modulators of Hedgehog signaling
U.S. Department of Health & Human Services —
Small-molecule antagonists of Hedgehog-pathway signaling, such as cyclopamine, have been known for some time. Now, small-molecule agonists of the Hedgehog pathway... -
Federal
Does Council Tax Valuation Band (CTVB) correlate with Under-Privileged Area 8 (UPA8) score and could it be a better 'Jarman Index'?
U.S. Department of Health & Human Services —
Background Widespread scepticism persists on the use of the Under-Privileged Area (UPA8) score of Jarman in distributing supplementary resources to so-attributed... -
Federal
Paper reports overview: The many guises of respiratory support, microalbuminuria and delirium
U.S. Department of Health & Human Services —
Paper reports overview: The many guises of respiratory support, microalbuminuria and delirium -
Federal
Homing chemokines in rheumatoid arthritis
U.S. Department of Health & Human Services —
In about 20% of patients with rheumatoid arthritis, B and T lymphocytes recruited into the inflamed synovium are organized into complex microstructures, which... -
Federal
Identifying research priorities on infections in older adults: proceedings of an interdisciplinary workshop
U.S. Department of Health & Human Services —
Background Infections pose a substantial burden to the health of older adults. In this report, we describe the proceedings of a workshop to formulate and prioritize... -
Federal
Adenosine preconditioning attenuates hepatic reperfusion injury in the rat by preventing the down-regulation of endothelial nitric oxide synthase
U.S. Department of Health & Human Services —
Background Previous work has suggested that in the liver, adenosine preconditioning is mediated by nitric oxide. Whether the endothelial isoform of nitric oxide... -
Federal
IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis
U.S. Department of Health & Human Services —
The origin and role of IL-17, a T-cell derived cytokine, in cartilage and bone destruction during rheumatoid arthritis (RA) remain to be clarified. In human ex vivo... -
Federal
Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of K
U.S. Department of Health & Human Services —
Background Phorbol 12-myristate 13-acetate (PMA) is often used as an activating phorbol ester of protein kinase C (PKC) to investigate the roles of the kinase in... -
Federal
Reduction of post injury neointima formation due to 17β-estradiol and phytoestrogen treatment is not influenced by the pure synthetic estrogen receptor antagonist ICI 182,780 in vitro
U.S. Department of Health & Human Services —
Background Animal and organ culture experiments have shown beneficial inhibitory estrogen effects on post injury neointima development. The purpose of this study was... -
Federal
The intein of the Thermoplasma A-ATPase A subunit: Structure, evolution and expression in
U.S. Department of Health & Human Services —
Background Inteins are selfish genetic elements that excise themselves from the host protein during post translational processing, and religate the host protein with...