2,009 datasets found
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Federal
Deficiency ofPtenaccelerates mammary oncogenesis in MMTV-Wnt-1transgenic mice
U.S. Department of Health & Human Services —
Germline mutations in the tumor suppressorPTENpredispose human beings to breast cancer, and genetic and epigenetic alterations ofPTENare also detected in sporadic... -
Federal
Association of MHC and rheumatoid arthritis:HLA polymorphisms in phenotypic variants of rheumatoid arthritis
U.S. Department of Health & Human Services —
Genes in the human leukocyte antigen (HLA) region remain the most powerful disease risk genes in rheumatoid arthritis (RA). Several allelic variants of HLA-DRB1 genes... -
Federal
Role of gammadelta T cells in protecting normal airway function
U.S. Department of Health & Human Services —
Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-... -
Federal
Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase
U.S. Department of Health & Human Services —
Background Epstein-Barr virus (EBV) infects resting B-lymphocytes and transforms them into immortal proliferating lymphoblastoid cell lines (LCLs) in vitro. The... -
Federal
Growth factors in idiopathic pulmonary fibrosis: relative roles
U.S. Department of Health & Human Services —
Treatment of idiopathic pulmonary fibrosis patients has evolved very slowly; the fundamental approach of corticosteroids alone or in combination with other... -
Federal
Craniodental variation among Macaques (
U.S. Department of Health & Human Services —
Background In terms of structure and function, the skull is one of the most complicated organs in the body. It is also one of the most important parts in terms of... -
Federal
Temperature measurement on neurological pulse generators during MR scans
U.S. Department of Health & Human Services —
According to manufacturers of both magnetic resonance imaging (MRI) machines, and implantable neurological pulse generators (IPGs), MRI is contraindicated for... -
Federal
Helium oxygen mixtures in the intensive care unit
U.S. Department of Health & Human Services —
Heliox, a mixture of helium and oxygen, has a density that is less than that of air. Breathing heliox leads to a reduction in resistance to flow within the airways,... -
Federal
Inhaled nitric oxide in acute respiratory distress syndrome with and without septic shock requiring norepinephrine administration: a dose–response study
U.S. Department of Health & Human Services —
Background: The aim of this prospective study was to assess whether the presence of septic shock could influence the dose response to inhaled nitric oxide (NO) in NO-... -
Federal
A comparison between two brine shrimp assays to detect
U.S. Department of Health & Human Services —
Background The brine shrimp lethality assay is considered a useful tool for preliminary assessment of toxicity. It has also been suggested for screening... -
Federal
Prescribing patterns in premenstrual syndrome
U.S. Department of Health & Human Services —
Background Over 300 therapies have been proposed for premenstrual syndrome. To date there has been only one survey conducted in the UK of PMS treatments prescribed by... -
Federal
Lack of microbiological concordance between bone and non-bone specimens in chronic osteomyelitis: an observational study
U.S. Department of Health & Human Services —
Background Prognosis of chronic osteomyelitis depends heavily on proper identification and treatment of the bone-infecting organism. Current knowledge on selecting... -
Federal
The Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trial
U.S. Department of Health & Human Services —
Previous trials (Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure [MERIT-HF], Cardiac Insufficiency Bisoprolol Study [CIBIS] II) have... -
Federal
Detection and subtyping of Herpes simplex virus in clinical samples by LightCycler PCR, enzyme immunoassay and cell culture
U.S. Department of Health & Human Services —
Background Prompt laboratory diagnosis of Herpes simplex virus (HSV) infection facilitates patient management and possible initiation of antiviral therapy. In our... -
Federal
Cingulate cortex hypoperfusion predicts Alzheimer's disease in mild cognitive impairment
U.S. Department of Health & Human Services —
Background Mild cognitive impairment (MCI) was recently described as a heterogeneous group with a variety of clinical outcomes and high risk to develop Alzheimer's... -
Federal
Preconceptional factors associated with very low birthweight delivery in East and West Berlin: a case control study
U.S. Department of Health & Human Services —
Background Very low birthweight, i.e. a birthweight < 1500 g, is among the strongest determinants of infant mortality and childhood morbidity. To develop primary... -
Federal
Differential expression of Aquaporin 8 in human colonic epithelial cells and colorectal tumors
U.S. Department of Health & Human Services —
Background The gene expression pattern in tumor cells differs from that in corresponding normal cells. In order to identify differentially expressed genes in... -
Federal
Role of delta-tubulin and the C-tubule in assembly of
U.S. Department of Health & Human Services —
Background A breakthrough in the understanding of centriole assembly was provided by the characterization of the UNI3 gene in Chlamydomonas. Deletion of this gene,... -
Federal
A case of central nervous system vasculitis related to an episode of Guillain-Barrè syndrome
U.S. Department of Health & Human Services —
The authors report their knowledge about an uncommon case of isolated vasculitis, restricted to the left sylvian artery during an auto-immune Guillain-Barrè syndrome... -
Federal
Complex trait analysis of the mouse striatum: independent QTLs modulate volume and neuron number
U.S. Department of Health & Human Services —
Background The striatum plays a pivotal role in modulating motor activity and higher cognitive function. We analyzed variation in striatal volume and neuron number in...
2,009 datasets found