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Federal
Updating a systematic review – what difference did it make? Case study of nicotine replacement therapy
U.S. Department of Health & Human Services —
Aims To examine the effect of updating a systematic review of nicotine replacement therapy on its contents and conclusions. Methods We examined the effects of regular... -
Federal
Genome trees constructed using five different approaches suggest new major bacterial clades
U.S. Department of Health & Human Services —
Background The availability of multiple complete genome sequences from diverse taxa prompts the development of new phylogenetic approaches, which attempt to... -
Federal
Benefits and side effects of blood pressure lowering treatment: what was wrong with doxazosin in the ALLHAT?
U.S. Department of Health & Human Services —
The lowering of high blood pressure is supposed to protect target organs from hypertensive damage. The Antihypertensive and Lipid Lowering Treatment to Prevent Heart... -
Federal
Klippel-Feil syndrome – the risk of cervical spinal cord injury: A case report
U.S. Department of Health & Human Services —
Background Klippel-Feil syndrome is defined as congenital fusion of two or more cervical vertebrae and is believed to result from faulty segmentation along the... -
Federal
How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-Up Study (Syst-Eur 2)
U.S. Department of Health & Human Services —
Background The randomised, double-blind, placebo-controlled Systolic Hypertension in Europe trial (Syst-Eur 1) proved that blood pressure (BP) lowering therapy... -
Federal
Evolutionary conservation of
U.S. Department of Health & Human Services —
Background Homeobox genes of the orthodenticle (otd)/Otx family have conserved roles in the embryogenesis of head and brain. Gene replacement experiments show that... -
Federal
Detection of chromosomes tagged with green fluorescent protein in live
U.S. Department of Health & Human Services —
Background Structural and dynamic studies of chromosomes tagged with green fluorescent protein (GFP) in yeast and cultured animal cells have revealed some surprises.... -
Federal
Oral health behavior patterns among Tanzanian university students: a repeat cross-sectional survey
U.S. Department of Health & Human Services —
Purpose This study examines oral health behavioral trends and the development of sociodemographic differences in oral health behaviors among Tanzanian students... -
Federal
In vivo involvement of polymorphonuclear neutrophils in Leishmania infantum infection
U.S. Department of Health & Human Services —
Background The role of lymphocytes in the specific defence against L. infantum has been well established, but the part played by polynuclear neutrophil (PN) cells in... -
Federal
A Prospective Study of Pravastatin in the Elderly at Risk (PROSPER): Screening Experience and Baseline Characteristics
U.S. Department of Health & Human Services —
Background PROSPER was designed to investigate the benefits of treatment with pravastatin in elderly patients for whom a typical doctor might consider the... -
Federal
Why do antioxidants fail to provide clinical benefit?
U.S. Department of Health & Human Services —
The results of recent randomized trials to test the influence of antioxidants on coronary-event rates and prognosis in patients with coronary-artery disease were... -
Federal
A new device for 100 per cent humidification of inspired air
U.S. Department of Health & Human Services —
A new humidifier for use during mechanical ventilation in endotracheally intubated patients is described and tested. The humidifier is based on a heat-moisture... -
Federal
The validity of self-reported weight in US adults: a population based cross-sectional study
U.S. Department of Health & Human Services —
Background Investigating the validity of the self-reported values of weight allows for the proper assessment of studies using questionnaire-derived data. The study... -
Federal
Socio-demographic factors and self-reported funtional status: the significance of social support
U.S. Department of Health & Human Services —
Background The aim of the present work was to investigate the relative importance of socio-demographic and physical health status factors for subjective functioning,... -
Federal
Effects of testicular microlithiasis on Doppler parameters: report of three cases
U.S. Department of Health & Human Services —
Background Testicular microlithiasis is a rare, usually asymptomatic, non-progressive disease of the testes associated with various genetic anomalies, infertility and... -
Federal
Model-based cluster analysis of microarray gene-expression data
U.S. Department of Health & Human Services —
Background Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data.... -
Federal
A quantitative PCR (TaqMan) assay for pathogenic
U.S. Department of Health & Human Services —
Background Leptospirosis is an emerging infectious disease. The differential diagnosis of leptospirosis is difficult due to the varied and often "flu like" symptoms... -
Federal
Reviewing the reviewers: the vague accountability of research ethics committees
U.S. Department of Health & Human Services —
The role of research ethics committees (RECs) is currently strained by increases in the number of protocols that are in need of review, the scientific and funding... -
Federal
A comprehensive analysis of 40 blind protein structure predictions
U.S. Department of Health & Human Services —
Background We thoroughly analyse the results of 40 blind predictions for which an experimental answer was made available at the fourth meeting on the critical... -
Federal
The genetics of rheumatoid arthritis and the need for animal models to find and understand the underlying genes
U.S. Department of Health & Human Services —
The causes of rheumatoid arthritis (RA) are largely unknown. However, RA is most probably a multifactorial disease with contributions from genetic and environmental...