2,009 datasets found
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Federal
A PCR-mutagenesis strategy for rapid detection of mutations in codon 634 of the
U.S. Department of Health & Human Services —
Background Multiple endocrine neoplasias type 2A (MEN 2A) is a dominantly inherited cancer syndrome. Missence mutations in the codon encoding cysteine 634 of the ret... -
Federal
Mechanical ventilation in rural ICUs
U.S. Department of Health & Human Services —
Background: In recent years, rural hospitals have expanded their scope of specialized services, which has led to the development and staffing of rural intensive care... -
Federal
Skeletal muscle dysfunction in chronic obstructive pulmonary disease
U.S. Department of Health & Human Services —
It has become increasingly recognized that skeletal muscle dysfunction is common in patients with chronic obstructive pulmonary disease (COPD). Muscle strength and... -
Federal
Bone morphogenetic protein-2 (BMP-2) and transforming growth factor-β1 (TGF-β1) alter connexin 43 phosphorylation in MC3T3-E1 Cells
U.S. Department of Health & Human Services —
Background Bone morphogenetic proteins (BMPs) and transforming growth factor-βs (TGF-βs) are important regulators of bone repair and regeneration. BMP-2 and TGF-β1... -
Federal
Color transitions in coral's fluorescent proteins by site-directed mutagenesis
U.S. Department of Health & Human Services —
Background Green Fluorescent Protein (GFP) cloned from jellyfish Aequorea victoria and its homologs from corals Anthozoa have a great practical significance as in... -
Federal
The enhancement of the hyperglycemic effect of S-nitrosoglutathione and S-nitroso-N-acetylpenicillamine by vitamin C in an animal model
U.S. Department of Health & Human Services —
Background S-nitrosoglutathione (GSNO) and S-nitroso-N-acetlypenicillamine (SNAP) are two of the most common sources of nitric oxide (NO) in the biomedical field.... -
Federal
Short-term LDL cholesterol-lowering efficacy of plant stanol esters
U.S. Department of Health & Human Services —
Background The short-term cholesterol-lowering efficacy of plant stanol esters has been open to debate, and the data from different clinical studies with... -
Federal
Are the pneumococcal polysaccharide vaccines effective? Meta-analysis of the prospective trials
U.S. Department of Health & Human Services —
The objective was to review the evidence of effectiveness of the polyvalent polysaccharide pneumococcal vaccine from prospective properly randomised controlled trials... -
Federal
House dust mite barrier bedding for childhood asthma: randomised placebo controlled trial in primary care [ISRCTN63308372]
U.S. Department of Health & Human Services —
Background The house dust mite is the most important environmental allergen implicated in the aetiology of childhood asthma in the UK. Dust mite barrier bedding is... -
Federal
Childhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses
U.S. Department of Health & Human Services —
The hygiene hypothesis states that childhood asthma develops as a result of decreased exposure to infectious agents during infancy and early childhood. This results... -
Federal
NEAT: a domain duplicated in genes near the components of a putative Fe
U.S. Department of Health & Human Services —
Iron uptake from the host is essential for bacteria that infect animals. A protein domain has been identified that appears in variable copy number in bacterial genes... -
Federal
What you should know about PR3-ANCA: An introduction
U.S. Department of Health & Human Services —
Anti-neutrophil cytoplasmic antibodies (ANCA) have become important diagnostic markers of small vessel vasculitides characterized by focal necrotizing lesions of... -
Federal
Estrogen receptor alpha dinucleotide repeat polymorphism in Japanese patients with autoimmune thyroid diseases
U.S. Department of Health & Human Services —
Background The autoimmune thyroid diseases (AITDs), comprising Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex... -
Federal
Consensus guidelines on analgesia and sedation in dying intensive care unit patients
U.S. Department of Health & Human Services —
Background Intensivists must provide enough analgesia and sedation to ensure dying patients receive good palliative care. However, if it is perceived that too much is... -
Federal
The therapeutic potential of modulators of the Hedgehog-Gli signaling pathway
U.S. Department of Health & Human Services —
The discovery of small molecules that act as agonists and antagonists of the Hedgehog-Gli signaling pathway, which plays important roles in the embryo and adult,... -
Federal
Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension
U.S. Department of Health & Human Services —
Several recent papers have shown that both familial primary pulmonary hypertension (FPPH) and sporadic primary pulmonary hypertension (PPH) may have a common etiology... -
Federal
What can we do about osteoarthritis?
U.S. Department of Health & Human Services —
Osteoarthritis is complex in genetics, pathogenesis, monitoring and treatment. Current treatment of osteoarthritis does not influence progression. Much could be... -
Federal
Statistics on continuous IBD data: Exact distribution evaluation for a pair of full(half)-sibs and a pair of a (great-) grandchild with a (great-) grandparent
U.S. Department of Health & Human Services —
Background Pairs of related individuals are widely used in linkage analysis. Most of the tests for linkage analysis are based on statistics associated with identity... -
Federal
Pulse oximetry
U.S. Department of Health & Human Services —
The human eye is poor at recognizing hypoxemia. Even under idealconditions, skilled observers cannot consistently detect hypoxemia until theoxygen (O2) saturation is... -
Federal
Risk factors for acquisition of hepatitis C virus infection: a case series and potential implications for disease surveillance
U.S. Department of Health & Human Services —
Background Transmission of hepatitis C vims (HCV) is strongly associated with use of contaminated blood products and injection drugs. Other "non-parental" modes of...
2,009 datasets found