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Federal
Effects of an angiotensin II antagonist on organ perfusion during the post-resuscitation phase in pigs
U.S. Department of Health & Human Services —
Background: The aim of this study was to compare pre-arrest and post-resuscitation organ perfusion values and to investigate whether, during the post-resuscitation... -
Federal
From fruitflies to mammals: mechanisms of signalling via the Sonic hedgehog pathway in lung development
U.S. Department of Health & Human Services —
The hedgehog signalling pathway has been implicated in many different processes in fly and vertebrate development. It is now known that the hedgehog cascade is... -
Federal
Alarms in the intensive care unit: how can the number of false alarms be reduced?
U.S. Department of Health & Human Services —
Many alarms, as they now exist in most monitoring systems, are not usually perceived as helpful by the medical staff because of the high incidence of false alarms.... -
Federal
A multinational randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis [ISRCTN25142273]
U.S. Department of Health & Human Services —
Background Etoricoxib is a highly selective COX-2 inhibitor which was evaluated for the treatment of rheumatoid arthritis (RA). Methods Double-blind, randomized,... -
Federal
Human airway xenograft models of epithelial cell regeneration
U.S. Department of Health & Human Services —
Regeneration and restoration of the airway epithelium after mechanical, viral or bacterial injury have a determinant role in the evolution of numerous respiratory... -
Federal
The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen, and combinations of these agents
U.S. Department of Health & Human Services —
Most anti-inflammatory drugs have been associated with an increased risk of serious upper gastrointestinal complications. Epidemiological studies have estimated the... -
Federal
Impaired wound healing in mice deficient in a matricellular protein SPARC (osteonectin, BM-40)
U.S. Department of Health & Human Services —
Background SPARC is a matricellular protein involved in cell-matrix interactions. From expression patterns at the wound site and in vitro studies, SPARC has been... -
Federal
Decreased levels of dehydroepiandrosterone sulphate in severe critical illness: a sign of exhausted adrenal reserve?
U.S. Department of Health & Human Services —
Introduction Dehydroepiandrosterone (DHEA) and its sulphate (DHEAS) are pleiotropic adrenal hormones with immunostimulating and antiglucocorticoid effects. The... -
Federal
Cardiac rehabilitation: a comprehensive review
U.S. Department of Health & Human Services —
Cardiac rehabilitation (CR) is a commonly used treatment for men and women with cardiovascular disease. To date, no single study has conclusively demonstrated a... -
Federal
Physician perceptions of primary prevention: qualitative base for the conceptual shaping of a practice intervention tool
U.S. Department of Health & Human Services —
Background A practice intervention must have its basis in an understanding of the physician and practice to secure its benefit and relevancy. We used a formative... -
Federal
Diagnostic value of gas exchange tests in patients with clinical suspicion of pulmonary embolism
U.S. Department of Health & Human Services —
Objective: To assess the value of parameters derived from arterial blood gas tests in the diagnosis of pulmonary embolism. Method: We measured alveolar-arterial... -
Federal
The 26thCongress of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine, Tromso, Norway, 13-17 June 2001
U.S. Department of Health & Human Services —
The Congress took place at the northernmost academic center in the world, in the state-of-the art Tromso University Hospital. There were over 500 participants, mainly... -
Federal
Joint effects of citrus peel use and black tea intake on the risk of squamous cell carcinoma of the skin
U.S. Department of Health & Human Services —
Background Differences in tea drinking habits and/or citrus peel use are likely to vary by populations and could contribute to the inconsistencies found between... -
Federal
Ileal mucosal bile acid absorption is increased in Cftr knockout mice
U.S. Department of Health & Human Services —
Background Excessive loss of bile acids in stool has been reported in patients with cystic fibrosis. Some data suggest that a defect in mucosal bile acid transport... -
Federal
Hormone replacement therapy and prevention of vertebral fractures: a meta-analysis of randomised trials
U.S. Department of Health & Human Services —
Background Hormone replacement therapy (HRT) is often seen as the treatment of choice for preventing fractures in women. We undertook a recent meta-analysis of... -
Federal
Identification of critical residues in loop E in the 5-HT
U.S. Department of Health & Human Services —
Background The serotonin type 3 receptor (5-HT3R) is a member of a superfamily of ligand gated ion channels. All members of this family share a large degree of... -
Federal
Evolution of gene order conservation in prokaryotes
U.S. Department of Health & Human Services —
Background As more complete genomes are sequenced, conservation of gene order between different organisms is emerging as an informative property of the genomes.... -
Federal
Reactivation of a silenced
U.S. Department of Health & Human Services —
Background The active copy of the imprinted gene H19 is turned off by inappropriate methylation in several pediatric tumors including Wilms' Tumour and embryonal... -
Federal
Pooling data for Number Needed to Treat: no problems for apples
U.S. Department of Health & Human Services —
Objective To consider the problem of the calculation of number needed to treat (NNT) derived from risk difference, odds ratio, and raw pooled events shown to give... -
Federal
A Review of the Adverse Effects of Peripheral Alpha-1 Antagonists in Hypertension Therapy
U.S. Department of Health & Human Services —
Background Doxazosin and its role as an antihypertensive agent have come under recent scrutiny as a result of the early termination of that treatment arm in ALLHAT....