49 datasets found
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Federal
An environment with strong gravitational and magnetic field alterations synergizes to promote variations in Arabidopsis thaliana callus global transcriptional state
National Aeronautics and Space Administration —
Using diamagnetic levitation we have exposed A. thaliana in vitro callus cultures to five environments with different levels of effective gravity (from levitation... -
Federal
Transcription profiling of Drosophila after exposure to microgravity in the International Space Station and in a microgravity simulator
National Aeronautics and Space Administration —
Larvae-Pupae transition flies (Drosophila) were recovered and transport for 3 days at 12-14C to arrest development until the launch site then exposed to RT (18-20C)... -
Federal
Identifying radiation exposure biomarkers from mouse blood transcriptome
National Aeronautics and Space Administration —
Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological... -
Federal
Bystander response to 2.5 Gy of protons in a human 3-dimensional skin model in 16 h after exposure
National Aeronautics and Space Administration —
Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling.... -
Federal
IMR90 4hr bystander experiment 0.5Gy alpha particle strip dish format
National Aeronautics and Space Administration —
Radiation affects tissue and cellular integrity at the level of DNA protein and metabolites of the cell and extracellular space. The effects of radiation are not... -
Federal
Human skin fibroblast mitochondrial depletion 0.5 Gy alpha-particle
National Aeronautics and Space Administration —
Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of... -
Federal
Gene expression profiling of C. elegans under various thermal conditions
National Aeronautics and Space Administration —
To realistically evaluate the effects of the environment in space it is necessary to understand the effects of external factors during sample transport from Earth to... -
Federal
Non-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis
National Aeronautics and Space Administration —
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4... -
Federal
Transcription profiling of human peripheral blood to development gene expression signatures for practical radiation biodosimetry
National Aeronautics and Space Administration —
To further development of our gene expression approach to biodosimetry we have employed whole genome microarray expression profiling as a discovery platform to...
49 datasets found