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Federal
Identification of candidate downstream genes for the homeodomain transcription factor Labial in
U.S. Department of Health & Human Services —
Background: Homeotic genes are key developmental regulators that are highly conserved throughout evolution. Their encoded homeoproteins function as transcription... -
Federal
Screening an alternative flame retardant using biological and transcriptomic endpoints in fish embryos
U.S. Environmental Protection Agency —
GEO accession information for omics RNA-seq data. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding... -
Federal
A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics
U.S. Environmental Protection Agency —
The U.S. Tox21 Federal collaboration, which currently quantifies the biological effects of nearly 10,000 chemicals via quantitative high-throughput screening(qHTS) in... -
Federal
Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins
U.S. Department of Health & Human Services —
Background NGF exerts a variety of actions including promotion of neuronal differentiation and survival. The PC12 rat pheochromocytoma cell line has proved valuable... -
Federal
Supervised harvesting of expression trees
U.S. Department of Health & Human Services —
Background We propose a new method for supervised learning from gene expression data. We call it 'tree harvesting'. This technique starts with a hierarchical... -
Federal
Permutation-validated principal components analysis of microarray data
U.S. Department of Health & Human Services —
Background In microarray data analysis, the comparison of gene-expression profiles with respect to different conditions and the selection of biologically interesting... -
Federal
Plant Expression Database
Department of Agriculture —
[NOTE: PLEXdb is no longer available online. Oct 2019.] PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens.... -
Federal
Evolutionary conservation of
U.S. Department of Health & Human Services —
Background Homeobox genes of the orthodenticle (otd)/Otx family have conserved roles in the embryogenesis of head and brain. Gene replacement experiments show that... -
Federal
Model-based cluster analysis of microarray gene-expression data
U.S. Department of Health & Human Services —
Background Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data.... -
Federal
Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer
U.S. Department of Health & Human Services —
Background Drug resistance in breast cancer is a major obstacle to successful chemotherapy. In this study we used cDNA microarray technology to examine gene... -
Federal
Differential expression of Aquaporin 8 in human colonic epithelial cells and colorectal tumors
U.S. Department of Health & Human Services —
Background The gene expression pattern in tumor cells differs from that in corresponding normal cells. In order to identify differentially expressed genes in... -
Federal
Gene-expression profiling of the response of peripheral blood mononuclear cells and melanoma metastases to systemic IL-2 administration
U.S. Department of Health & Human Services —
Early changes in transcriptional profiles of circulating mononuclear cells were compared with those occurring within the microenvironment of melanoma metastases... -
Federal
PRESTA: associating promoter sequences with information on gene expression
U.S. Department of Health & Human Services —
The software tool PRESTA (PRomoter EST Association) is designed for efficient recovery of characterized and partially verified promoters from GenBank and EMBL... -
Federal
Poly purine.pyrimidine sequences upstream of the beta-galactosidase gene affect gene expression in
U.S. Department of Health & Human Services —
Background Poly purine.pyrimidine sequences have the potential to adopt intramolecular triplex structures and are overrepresented upstream of genes in eukaryotes.... -
Federal
Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals
U.S. Department of Health & Human Services —
Background Expression profiling holds great promise for rapid host genome functional analysis. It is plausible that host expression profiling in an infection could... -
Federal
How many replicates of arrays are required to detect gene expression changes in microarray experiments? A mixture model approach
U.S. Department of Health & Human Services —
Background It has been recognized that replicates of arrays (or spots) may be necessary for reliably detecting differentially expressed genes in microarray... -
Federal
A glutamine-amidotransferase-like protein modulates FixT anti-kinase activity in
U.S. Department of Health & Human Services —
Background Nitrogen fixation gene expression in Sinorhizobium meliloti, the alfalfa symbiont, depends on a cascade of regulation that involves both positive and... -
Federal
Identification ofSchistosoma mansonigender-associated gene transcripts by cDNA microarray profiling
U.S. Department of Health & Human Services —
Parasitic helminths of the genusSchistosomamate, achieve sexual maturity and produce eggs in the bloodstream of their definitive hosts, and the most important... -
Federal
Evidence for large domains of similarly expressed genes in the
U.S. Department of Health & Human Services —
Background Transcriptional regulation in eukaryotes generally operates at the level of individual genes. Regulation of sets of adjacent genes by mechanisms operating... -
Federal
The major transcription initiation site of the
U.S. Department of Health & Human Services —
Background The cyclin-dependent kinase inhibitor p27Kip1 is essential for proper control of cell cycle progression. The levels of p27Kip1 are regulated by several...