2,009 datasets found
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Federal
Design and implementation of microarray gene expression markup language (MAGE-ML)
U.S. Department of Health & Human Services —
Meaningful exchange of microarray data is currently difficult because it is rare that published data provide sufficient information depth or are even in the same... -
Federal
A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes
U.S. Department of Health & Human Services —
Background: Correlations between genome composition (in terms of GC content) and usage of particular codons and amino acids have been widely reported, but poorly... -
Federal
Activation of the peroxisome proliferator-activated receptor α protects against myocardial ischaemic injury and improves endothelial vasodilatation
U.S. Department of Health & Human Services —
Background The peroxisome proliferator-activated receptor α (PPARα) plays an important role in the metabolism of lipoproteins and fatty acids, and seems to protect... -
Federal
Tumor necrosis factor-α and muscle wasting: a cellular perspective
U.S. Department of Health & Human Services —
Tumor necrosis factor-α (TNF-α) is a polypeptide cytokine that has been associated with muscle wasting and weakness in inflammatory disease. Despite its potential... -
Federal
The high-risk surgical patient revisited
U.S. Department of Health & Human Services —
The high-risk surgical patient revisited -
Federal
Icodextrin as salvage therapy in peritoneal dialysis patients with refractory fluid overload
U.S. Department of Health & Human Services —
Background Icodextrin is a high molecular weight, starch-derived glucose polymer, which is capable of inducing sustained ultrafiltration over prolonged (12–16 hour)... -
Federal
Heart rate changes during partial seizures: A study amongst Singaporean patients
U.S. Department of Health & Human Services —
Introduction Studies in Europe and America showed that tachycardia, less often bradycardia, frequently accompanied partial seizures in Caucasian patients. We... -
Federal
Genetic transformation of
U.S. Department of Health & Human Services —
Background Efficient transformation and regeneration methods are a priority for successful application of genetic engineering to vegetative propagated plants such as... -
Federal
Airway pressure release ventilation increases cardiac performance in patients with acute lung injury/adult respiratory distress syndrome
U.S. Department of Health & Human Services —
Background The purpose of the present study is to determine whether airway pressure release ventilation (APRV) can safely enhance hemodynamics in patients with acute... -
Federal
Implications of recent hypertension trials for the generalist physician: whom do we treat, and how?
U.S. Department of Health & Human Services —
The publication of the results of the Swedish Trial in Old Patients with Hypertension-2 (STOP-2) and the termination of the doxazocin arm of the Antihypertensive and... -
Federal
Anti-atherogenic effects of fibrates in type 2 diabetes
U.S. Department of Health & Human Services —
Type 2 diabetes is an increasing cause of premature coronary heart disease. Several trials with lipid-modifying therapy have included sufficient numbers of diabetics... -
Federal
The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B distribution
U.S. Department of Health & Human Services —
Background Growth inhibition by RPR-130401, a non-peptidomimetic farnesyltransferase inhibitor, was investigated without or with combined exposure to ionizing... -
Federal
Molecular archeology of L1 insertions in the human genome
U.S. Department of Health & Human Services —
A detailed analysis of the anatomy and distribution of L1 elements in the human genome was carried out using a new computer program, TSDfinder, designed to identify... -
Federal
The role of neuraminidase inhibitors in the treatment and prevention of influenza
U.S. Department of Health & Human Services —
The role of neuraminidase inhibitors in the treatment and prevention of influenza -
Federal
Genomic analysis of membrane protein families: abundance and conserved motifs
U.S. Department of Health & Human Services —
A genome-wide analysis was carried out on patterns of the classified polytopic membrane protein families, and the distribution of conserved amino acids and motifs in... -
Federal
Airway obstruction in asthma: does the response to a deep inspiration matter?
U.S. Department of Health & Human Services —
Airway hyperresponsiveness in asthma may not be a problem of too much airway smooth muscle strength. Rather, it may be a problem of too little of the factors that... -
Federal
Research Article: Journal of Biomedicine and Biotechnology
U.S. Department of Health & Human Services —
Tamoxifen, a potent anticancer agent known to interrupt the enhanced estrogen activity of malignant mammary gland cells, was recently approved by the Food and Drug... -
Federal
The intronic G13964C variant in
U.S. Department of Health & Human Services —
Background Mutations in BRCA1 and BRCA2 account for approximately 50% of breast cancer families with more than four affected cases, whereas exonic mutations in p53,... -
Federal
Lipoprotein profile in older patients with vascular dementia and Alzheimer's disease
U.S. Department of Health & Human Services —
Background Some alterations of the lipoprotein profile have been associated with cerebrovascular disease. Recently, it has been suggested that cerebrovascular disease... -
Federal
Pacing in congestive heart failure
U.S. Department of Health & Human Services —
Despite the major advances in medical drug therapy, heart failure remains a syndrome associated with high mortality and morbidity. Biventricular or left ventricular...
2,009 datasets found