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Federal
Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset
U.S. Department of Health & Human Services —
An inception cohort of 238 patients having peripheral joint synovitis of less than 12 months duration was evaluated clinically and followed prospectively for 1 year... -
Federal
Possible attenuation of the G2 DNA damage cell cycle checkpoint in HeLa cells by extremely low frequency (ELF) electromagnetic fields
U.S. Department of Health & Human Services —
Background The issue remains unresolved as to whether low frequency magnetic fields can affect cell behaviour, with the possibility that they may be in part... -
Federal
A direct method to visualise the aryl acylamidase activity on cholinesterases in polyacrylamide gels
U.S. Department of Health & Human Services —
Background In vertebrates, two types of cholinesterases exist, acetylcholinesterase and butyrylcholinesterase. The function of acetylcholinesterase is to hydrolyse... -
Federal
A revival of the B cell paradigm for rheumatoid arthritis pathogenesis?
U.S. Department of Health & Human Services —
Dominant paradigms for the understanding of rheumatoid arthritis (RA) pathogenesis have changed over the years. A predominant role of B lymphocytes, and perhaps of... -
Federal
Cdc5 influences phosphorylation of Net1 and disassembly of the RENT complex
U.S. Department of Health & Human Services —
Background In S. cerevisiae, the mitotic exit network (MEN) proteins, including the Polo-like protein kinase Cdc5 and the protein phosphatase Cdc14, are required for... -
Federal
Epithelial antimicrobial peptides in host defense against infection
U.S. Department of Health & Human Services —
One component of host defense at mucosal surfaces seems to be epithelium-derived antimicrobial peptides. Antimicrobial peptides are classified on the basis of their... -
Federal
The Adaptive Evolution Database (TAED)
U.S. Department of Health & Human Services —
Background The Master Catalog is a collection of evolutionary families, including multiple sequence alignments, phylogenetic trees and reconstructed ancestral... -
Federal
Stroke in urban and rural populations in north-east Bulgaria: incidence and case fatality findings from a 'hot pursuit' study
U.S. Department of Health & Human Services —
Background Bulgaria's official stroke mortality rates are higher for rural than urban areas. Official mortality data has indicated that these rates are amongst the... -
Federal
Venous oxygen measurements in the inferior vena cava in neonates with respiratory failure
U.S. Department of Health & Human Services —
Background: The present study was undertaken to examine the feasibility of venous oxygen measurements in the inferior vena cava (IVC) via a catheter through the... -
Federal
Plasma proteins in a standardised skin mini-erosion (II): effects of extraction pressure
U.S. Department of Health & Human Services —
Background A standardised suction technique has been used to sample plasma proteins in dermal interstitial fluid (IF) serially for 5 to 6 days from a suction-induced... -
Federal
Dynamic contrast-enhanced magnetic resonance imaging of the sarcopenic muscle
U.S. Department of Health & Human Services —
Background Studies about capillarity of the aged muscle provided conflicting results and no data are currently available about the magnetic resonance imaging (MRI) in... -
Federal
Cellophane based mini-prep method for DNA extraction from the filamentous fungus
U.S. Department of Health & Human Services —
Background Methods for the extraction of DNA from filamentous fungi are frequently laborious and time consuming because most of the available protocols include... -
Federal
Simultaneous identification of
U.S. Department of Health & Human Services —
Background The glutathione S-transferase (GST) enzyme GSTP1 utilizes byproducts of oxidative stress. We previously showed that alleles of GSTP1 that encode the... -
Federal
Specificity of DNA triple helix formation analyzed by a FRET assay
U.S. Department of Health & Human Services —
Background A third DNA strand can bind into the major groove of a homopurine duplex DNA to form a DNA triple helix. Sequence specific triplex formation can be applied... -
Federal
The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung disease
U.S. Department of Health & Human Services —
Secretory leukocyte proteinase inhibitor and elafin are two low-molecular-mass elastase inhibitors that are mainly synthesized locally at mucosal sites. It is thought... -
Federal
Potential role and chronology of abnormal expression of the Deleted in Colon Cancer (DCC) and the p53 proteins in the development of gastric cancer
U.S. Department of Health & Human Services —
Background Loss of activity of tumor suppressor genes is considered a fundamental step in a genetic model of carcinogenesis. Altered expression of the p53 and the... -
Federal
Regulation of prostaglandin synthesis and cell adhesion by a tryptophan catabolizing enzyme
U.S. Department of Health & Human Services —
Background The tryptophan catabolizing enzyme, indoleamine 2,3, dioxygenase (IDO) is one of two mammalian enzymes, which can catabolize the rarest essential amino... -
Federal
Dynamic diversity of the tryptophan pathway in chlamydiae: reductive evolution and a novel operon for tryptophan recapture
U.S. Department of Health & Human Services —
The factors that accommodate the transition of different chlamydial species to the persistent state of pathogenesis include marked differences in the strategied... -
Federal
Treating patients with low high-density lipoprotein cholesterol: choices, issues and opportunities
U.S. Department of Health & Human Services —
Three clinical trials have recently focused on the benefits of lipid-regulating therapy in populations with normocholesterolaemia and low high-density lipoprotein... -
Federal
Effects of leucine supplemented diet on intestinal absorption in tumor bearing pregnant rats
U.S. Department of Health & Human Services —
Background It is known that amino acid oxidation is increased in tumor-bearing rat muscles and that leucine is an important ketogenic amino acid that provides energy...