63 datasets found
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Federal
Effects of bedrest and hypoxia on human skeletal muscle miRNA expression
National Aeronautics and Space Administration —
The present study concerns the effects of 21 days of sustained recumbence (bedrest) and hypoxia alone and in combination on skeletal muscle microRNA expression. 14... -
Federal
HARV replication of the BRIC-21 Bacillus subtilis spaceflight samples
National Aeronautics and Space Administration —
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This... -
Federal
Exposure of zebrafish larvae to relative microgravity between 5-6 days post-fertilization
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors with a special emphasis on bone formation. For this reason... -
Federal
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity
National Aeronautics and Space Administration —
Efficient generation of cardiomyocytes from human pluripotent stem cells is critical for their regenerative applications. Microgravity and 3D culture can profoundly... -
Federal
Exposure of zebrafish larvae to 3g and 5g hyper gravity between 5-6 days post-fertilization.
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors with a special emphasis on bone formation. For this reason... -
Federal
Effect of a 91 day long stay in weightlessness on the International Space Station on mouse skin physiology
National Aeronautics and Space Administration —
Comparitive gene expression in skin between mice maintained in microgravity (0g) and normogravity (1g) environment. Six male C57Bl/J10 mice were housed for 91 days in... -
Federal
Methylome Analysis of Arabidopsis Seedlings Exposed to Microgravity
National Aeronautics and Space Administration —
DNA methylation is a very important kind of epigenetic modification and participates in many biological functions. Although many previous studies have addressed... -
Federal
Response of the EPI-200 human 3-D skin model to high and low doses of protons
National Aeronautics and Space Administration —
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose... -
Federal
Transcription profiling of atm mutant adm mutant and wild type whole plants and roots of Arabidopsis after gamma ray irradiation in a time series
National Aeronautics and Space Administration —
Whole seedlings of wild type (4d) and atm mutants (4d) have been analyzed after a gamma ray irradiation of 0.75h 1.5h 3h & 5h (time course). Roots of wt (4d) atm... -
Federal
A whole-genome microarray study of Arabidopsis thaliana cell cultures exposed to microgravity for 5 days on board of Shenzhou 8
National Aeronautics and Space Administration —
Arabidopsis thaliana wild type cell cultures were exposed to a 5-day space flight onboard of Shenzhou 8 to identify microgravity and space effect related gene... -
Federal
Gene expression response to simulated gravity and hypergravity in human T cells
National Aeronautics and Space Administration —
We investigated differentially regulated and stably expressed genes in human Jurkat T lymphocytic cells in 5min simulated microgravity and hypergravity and compared... -
Federal
Exposure of zebrafish larvae to relative microgravity between 5-6 days post-fertilization
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors with a special emphasis on bone formation. For this reason... -
Federal
Zebrafish larvae submitted to simulated microgravity on a clinostat (CLINO) at 5dpf for one day
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special... -
Federal
miRNA signature detection and countermeasures against HZE radiation exposure for tissue degeneration-Soleus muscle
National Aeronautics and Space Administration —
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA... -
Federal
Eruca sativa Rocket Science RNA-seq
National Aeronautics and Space Administration —
In the Rocket Science citizen science project Eruca sativa (salad rocket) seeds stored for six months on board of the International Space Station caused delayed crop... -
Federal
Global gene expression profiling of radiation-induced rat mammary carcinomas
National Aeronautics and Space Administration —
To investigate gene expression patterns in rat mammary carcinomas induced by ionizing radiation. Gene expression patterns were analyzed in radiation-induced rat... -
Federal
Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station
National Aeronautics and Space Administration —
In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose... -
Federal
Effects of 21 days of bedrest on human skeletal muscle gene expression
National Aeronautics and Space Administration —
The present study concerns the effects of 21 days of sustained recumbence (bedrest) on skeletal muscle gene expression. 14 male subjects participated in normoxic... -
Federal
Transcription profiling of mouse osteoblasts under static vs simulated microgravity
National Aeronautics and Space Administration —
The total RNA was extracted from 2T3 pre-osteoblast cells exposed to static or simulated microgravity (Rotating Wall Vessel) conditions. The RNA was then sent to... -
Federal
Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station
National Aeronautics and Space Administration —
In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose...
63 datasets found