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Federal
Little qualitative RNA misexpression in sterile male F
U.S. Department of Health & Human Services —
Background Although the genetics of hybrid sterility has been the subject of evolutionary studies for over sixty years, no one has shown the reason(s) why alleles... -
Federal
Sources of nonlinearity in cDNA microarray expression measurements
U.S. Department of Health & Human Services —
Background A key assumption in the analysis of microarray data is that the quantified signal intensities are linearly related to the expression levels of the... -
Federal
Analysis of strain and regional variation in gene expression in mouse brain
U.S. Department of Health & Human Services —
Background We performed a statistical analysis of a previously published set of gene expression microarray data from six different brain regions in two mouse strains.... -
Federal
Efficacy of SSH PCR in isolating differentially expressed genes
U.S. Department of Health & Human Services —
Background Suppression Subtractive Hybridization PCR (SSH PCR) is a sophisticated cDNA subtraction method to enrich and isolate differentially expressed genes.... -
Federal
Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application
U.S. Department of Health & Human Services —
Background A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic... -
Federal
New feature subset selection procedures for classification of expression profiles
U.S. Department of Health & Human Services —
Background Methods for extracting useful information from the datasets produced by microarray experiments are at present of much interest. Here we present new methods... -
Federal
Normalization and analysis of DNA microarray data by self-consistency and local regression
U.S. Department of Health & Human Services —
A robust semi-parametric normalization technique has been developed, based on the assumption that the large majority of genes will not have their relative expression... -
Federal
Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation
U.S. Department of Health & Human Services —
The aim of this study was to explore the molecular profile of proliferating rheumatoid arthritis synovial fibroblasts (RA-SF). Total RNA was extracted from two... -
Federal
Profound effect of normalization on detection of differentially expressed genes in oligonucleotide microarray data analysis
U.S. Department of Health & Human Services —
A number of procedures for normalization and detection of differentially expressed genes have been proposed. Four different normalization methods and all possible... -
Federal
Design and implementation of microarray gene expression markup language (MAGE-ML)
U.S. Department of Health & Human Services —
Meaningful exchange of microarray data is currently difficult because it is rare that published data provide sufficient information depth or are even in the same... -
Federal
Data from: Impacts of gene duplication in the evolution of symbiotic root nodule symbiosis
Department of Agriculture —
The emerging consensus regarding the origin of root nodule symbiosis (RNS), based on modeling of trait gain and loss across approximately 13,000 species within the... -
Federal
Research Article: BMC Genomics
U.S. Department of Health & Human Services —
Background Gonadotropin releasing hormone (GnRH) is responsible for stimulation of gonadotropic hormone (GtH) in the hypothalamus-pituitary-gonadal axis (HPG). The... -
Federal
Survey of transcripts in the adult
U.S. Department of Health & Human Services —
Background: Classic methods of identifying genes involved in neural function include the laborious process of behavioral screening of mutagenized flies and then... -
Federal
Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location
U.S. Department of Health & Human Services —
Background Members of the ribonuclease III superfamily of double-stranded(ds)-RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways... -
Federal
Evaluation of normalization procedures for oligonucleotide array data based on spiked cRNA controls
U.S. Department of Health & Human Services —
Background Affymetrix oligonucleotide arrays simultaneously measure the abundances of thousands of mRNAs in biological samples. Comparability of array results is... -
Federal
HepRG exposed to microcystin LR and RR gene expression
U.S. Environmental Protection Agency —
RNA-seq data from HepaRG cells exposed for 2 hours to microcystin-LR and -RR at multiple concentrations each. This dataset is associated with the following... -
Federal
Data from: Gene expression during the early stages of host perception and attachment in adult female Rhipicephalus microplus ticks
Department of Agriculture —
This study produced a comprehensive transcriptome from newly molted adult ticks and will provide a useful resource for studies of tick feeding and host perception and... -
Federal
Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes
U.S. Department of Health & Human Services —
Background Thioredoxin reductase (TR) is a redox active protein involved in many cellular processes as part of the thioredoxin system. Presently there are three... -
Federal
Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays
U.S. Department of Health & Human Services —
A cell-culture model was used to establish a profile of gene expression during the effector phase of ceramide-mediated cell death. Of the 239 genes that met the... -
Federal
Receptor protein tyrosine kinase EphB4 is up-regulated in colon cancer
U.S. Department of Health & Human Services —
Background We have used commercially available cDNA arrays to identify EphB4 as a gene that is up-regulated in colon cancer tissue when compared with matched normal...