2,009 datasets found
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Federal
Cost effectiveness in treating ventilator-associated pneumonia
U.S. Department of Health & Human Services —
Ventilator-associated pneumonia is a common illness in intensive care unit patients. The costs of management are increased when infection involves resistant... -
Federal
MP20, the second most abundant lens membrane protein and member of the tetraspanin superfamily, joins the list of ligands of galectin-3
U.S. Department of Health & Human Services —
Background Although MP20 is the second most highly expressed membrane protein in the lens its function remains an enigma. Putative functions for MP20 have recently... -
Federal
The Myocardial Ischemia Reduction with Acute Cholesterol Lowering (MIRACL) trial: a new frontier for statins?
U.S. Department of Health & Human Services —
The Myocardial Ischemia Reduction with Acute Cholesterol Lowering (MIRACL) Trial tested the hypothesis that intensive lowering of cholesterol with atorvastatin (80... -
Federal
Improved analytical methods for microarray-based genome-composition analysis
U.S. Department of Health & Human Services —
Genome-composition analysis using microarrays can be used to categorize genes into 'present' and 'divergent' categories. This involves selecting a signal value that... -
Federal
Intraocular pressure in genetically distinct mice: an update and strain survey
U.S. Department of Health & Human Services —
Background Little is known about genetic factors affecting intraocular pressure (IOP) in mice and other mammals. The purpose of this study was to determine the IOPs... -
Federal
Observer variation in chest radiography of acute lower respiratory infections in children: a systematic review
U.S. Department of Health & Human Services —
Background Knowledge of the accuracy of chest radiograph findings in acute lower respiratory infection in children is important when making clinical decisions.... -
Federal
Analysis of stress- and host cell-induced expression of the
U.S. Department of Health & Human Services —
Background The gene encoding the inorganic pyrophosphatase (PPase) of the intracellular pathogen Legionella pneumophila is induced during intracellular infection, but... -
Federal
The effect of EGTA and Ca
U.S. Department of Health & Human Services —
Background The Na/K-ATPase activity of the brain synaptic plasma membranes (SPM) is regulated by noradrenaline (NA) and the synaptosomal factor SF (soluble protein... -
Federal
Evidence for an evolutionarily conserved interaction between cell wall biosynthesis and flowering in maize and sorghum
U.S. Department of Health & Human Services —
Background Factors that affect flowering vary among different plant species, and in the grasses in particular the exact mechanism behind this transition is not fully... -
Federal
A protein folding potential that places the native states of a large number of proteins near a local minimum
U.S. Department of Health & Human Services —
Background We present a simple method to train a potential function for the protein folding problem which, even though trained using a small number of proteins, is... -
Federal
Oxygen and nitrate-dependent regulation of
U.S. Department of Health & Human Services —
Background Escherichia coli can respire anaerobically using dimethyl sulfoxide (DMSO) or trimethylamine-N-oxide (TMAO) as the terminal electron acceptor for anaerobic... -
Federal
Systematic adjudication of myocardial infarction end-points in an international clinical trial
U.S. Department of Health & Human Services —
Background Clinical events committees (CEC) are used routinely to adjudicate suspected end-points in cardiovascular trials, but little information has been published... -
Federal
Little qualitative RNA misexpression in sterile male F
U.S. Department of Health & Human Services —
Background Although the genetics of hybrid sterility has been the subject of evolutionary studies for over sixty years, no one has shown the reason(s) why alleles... -
Federal
The new anti-actin agent dihydrohalichondramide reveals fenestrae-forming centers in hepatic endothelial cells
U.S. Department of Health & Human Services —
Background Liver sinusoidal endothelial cells (LSECs) react to different anti-actin agents by increasing their number of fenestrae. A new structure related to... -
Federal
IFN-gamma transgenic mice: clues to the pathogenesis of systemic lupus erythematosus?
U.S. Department of Health & Human Services —
Transgenic mice overexpressing IFN-γ in the epidermis develop an inflammatory skin disease resembling cutaneous lupus erythematosus shortly after birth. By 3 months... -
Federal
The current status of primary prevention in coronary heart disease
U.S. Department of Health & Human Services —
During the second part of the twentieth century, research advances caused a substantial decline in the rate of coronary heart disease. The decline lasted from the... -
Federal
Adolescent standing postural response to backpack loads: a randomised controlled experimental study
U.S. Department of Health & Human Services —
Background Backpack loads produce changes in standing posture when compared with unloaded posture. Although 'poor' unloaded standing posture has been related to... -
Federal
The Metal Coordination of sCD39 during ATP Hydrolysis
U.S. Department of Health & Human Services —
Background The hydrolysis of ATP and ADP by ecto-nucleoside triphosphate diphosphohydrolase 1 (CD39) requires divalent cations, like Ca2+ and Mg2+. In spite of... -
Federal
Pooling, meta-analysis, and the evaluation of drug safety
U.S. Department of Health & Human Services —
Background The "integrated safety report" of the drug registration files submitted to health authorities usually summarizes the rates of adverse events observed for a... -
Federal
A new model for rheumatoid arthritis?
U.S. Department of Health & Human Services —
A chance observation has led to the development of a new murine model for inflammatory arthritis. Arthritis is induced, and transferred, by T-cell-dependent...
2,009 datasets found