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Federal
New immunosuppressive drugs in heart transplantation
U.S. Department of Health & Human Services —
Only a few randomized clinical trials have been performed so far in heart transplant recipients, mainly because of the relatively small number of heart transplants... -
Federal
Gut oxygenation in sepsis: Still a matter of controversy?
U.S. Department of Health & Human Services —
Part of Stephan Jakob's exhaustive review paper in the present issue of Critical Care deals with the notion that intestinal cellular energetics are deranged in... -
Federal
Therapy of ankylosing spondylitis and other spondyloarthritides: established medical treatment, anti-TNF-α therapy and other novel approaches
U.S. Department of Health & Human Services —
Therapeutic options for patients with more severe forms of spondyloarthritis (SpA) have been rather limited in recent decades. There is accumulating evidence that... -
Federal
Autoantibodies directed to novel components of the PM/Scl complex, the human exosome
U.S. Department of Health & Human Services —
The autoantigenic polymyositis/scleroderma (PM/Scl) complex was recently shown to be the human homologue of the yeast exosome, which is an RNA-processing complex. Our... -
Federal
Supracervical hysterectomy versus total abdominal hysterectomy: perceived effects on sexual function
U.S. Department of Health & Human Services —
Background Our investigation sought to compare changes in sexual function following supracervical hysterectomy (SCH) and total abdominal hysterectomy (TAH). Methods A... -
Federal
Hospital competition, resource allocation and quality of care
U.S. Department of Health & Human Services —
Background A variety of approaches have been used to contain escalating hospital costs. One approach is intensifying price competition. The increase in price based... -
Federal
Safety of a new extensively hydrolysed formula in children with cow's milk protein allergy: a double blind crossover study
U.S. Department of Health & Human Services —
Background Formulae for infants with cow's milk protein allergy (CMA) should be based on extensively hydrolysed protein. 'Extensively' however is not strictly... -
Federal
Mitotic death: a mechanism of survival? A review
U.S. Department of Health & Human Services —
Mitotic death is a delayed response of p53 mutant tumours that are resistant to genotoxic damage. Questions surround why this response is so delayed and how its... -
Federal
The attributable mortality and length of intensive care unit stay of clinically important gastrointestinal bleeding in critically ill patients
U.S. Department of Health & Human Services —
Objective To estimate the mortality and length of stay in the intensive care unit (ICU) attributable to clinically important gastrointestinal bleeding in mechanically... -
Federal
The families evaluation on management, care and disclosure for terminal stage cancer patients
U.S. Department of Health & Human Services —
Background Quality of life is an important concept which is subjective and personal; what is an acceptable quality of life to one may be 'worse than death' to... -
Federal
Adenovirus type 7 associated with severe and fatal acute lower respiratory infections in Argentine children
U.S. Department of Health & Human Services —
Background Adenoviruses are the second most prevalent cause of acute lower respiratory infection of viral origin in children under four years of age in Buenos Aires,... -
Federal
"Bronchial Artery Delivery of Viral Vectors for Gene delivery in Cystic Fibrosis; Superior to Airway Delivery?"
U.S. Department of Health & Human Services —
Background Attempts at gene therapy for the pulmonary manifestations of Cystic Fibrosis have relied mainly on airway delivery. However the efficiency of gene transfer... -
Federal
Extracorporeal membrane oxygenation for overwhelming
U.S. Department of Health & Human Services —
Extracorporeal membrane oxygenation for overwhelming -
Federal
Non-enzymatic glycosylation of a type I collagen matrix: effects on osteoblastic development and oxidative stress
U.S. Department of Health & Human Services —
Background The tissue accumulation of protein-bound advanced glycation endproducts (AGE) may be involved in the etiology of diabetic chronic complications, including... -
Federal
Incidence and Characteristics of Total Stroke in the United States
U.S. Department of Health & Human Services —
Background and Purpose Stroke, increasingly referred to as a "brain attack", is one of the leading causes of death and the leading cause of adult disability in the... -
Federal
Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis
U.S. Department of Health & Human Services —
BALB/c mice immunized with human cartilage proteoglycan (PG) develop arthritis accompanied by the production of autoantibodies to mouse cartilage PG. To determine... -
Federal
Clinical ethics revisited
U.S. Department of Health & Human Services —
A decade ago, we reviewed the field of clinical ethics; assessed its progress in research, education, and ethics committees and consultation; and made predictions... -
Federal
Acute bilateral emphysematous pyelonephritis successfully managed by medical therapy alone: A case report and review of the literature
U.S. Department of Health & Human Services —
Background Bilateral emphysematous pyelonephritis is a life threatening condition usually occurring in diabetics. Management of this condition has traditionally been... -
Federal
Genomic organization and alternative splicing of the human and mouse RPTPρ genes
U.S. Department of Health & Human Services —
Background Receptor protein tyrosine phosphatase rho (RPTPρ, gene symbol PTPRT) is a member of the type IIB RPTP family. These transmembrane molecules have been... -
Federal
The International Sepsis Forum's controversies in sepsis: how will sepsis be treated in 2051?
U.S. Department of Health & Human Services —
Great advances have been made in describing the intracellular pathways and genes that are activated by bacterial products. New definitions and therapies for sepsis...