2,009 datasets found
-
Federal
Outcome of major cardiac injuries at a Canadian trauma center
U.S. Department of Health & Human Services —
Background Canadian trauma units have relatively little experience with major cardiac trauma (disruption of a cardiac chamber) so injury outcome may not be comparable... -
Federal
Salivary testosterone levels in preadolescent children
U.S. Department of Health & Human Services —
Background Saliva reflects the plasma free fraction of testosterone which is biologically active, and available for uptake by tissues. Testosterone concentration in... -
Federal
Androgen and retinoic acid interaction in LNCaP cells, effects on cell proliferation and expression of retinoic acid receptors and epidermal growth factor receptor
U.S. Department of Health & Human Services —
Background Modulation of the expression of retinoic acid receptors (RAR) α and γ in adult rat prostate by testosterone (T) suggests that RAR signaling events might... -
Federal
Macrophages in rheumatoid arthritis
U.S. Department of Health & Human Services —
The abundance and activation of macrophages in the inflamed synovial membrane/pannus significantly correlates with the severity of rheumatoid arthritis (RA). Although... -
Federal
Right and left prefrontal transcranial magnetic stimulation at 1 Hz does not affect mood in healthy volunteers
U.S. Department of Health & Human Services —
Background Prefrontal repetitive transcranial magnetic stimulation (rTMS) has been used to induce side-specific mood changes in volunteers and patients. To clarify... -
Federal
Experience collecting interim data on mortality: an example from the RALES study
U.S. Department of Health & Human Services —
Introduction The Randomized Aldactone Evaluation Study (RALES) randomized 822 patients to receive 25 mg spironolactone daily and 841 to receive placebo. The primary... -
Federal
Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels
U.S. Department of Health & Human Services —
Activity of voltage-gated potassium (Kv) channels controls membrane potential, which subsequently regulates cytoplasmic free calcium concentration ([Ca2+]cyt) in... -
Federal
The estimated economic burden of genital herpes in the United States. An analysis using two costing approaches
U.S. Department of Health & Human Services —
Background Only limited data exist on the costs of genital herpes (GH) in the USA. We estimated the economic burden of GH in the USA using two different costing... -
Federal
Hypothermia and neurologic outcome in patients following cardiac arrest: should we be hot to cool off our patients?
U.S. Department of Health & Human Services —
Hypothermia as a protectant of neurologic function in the treatment of cardiac arrest patients, although not a new concept, is now supported by two recent randomized,... -
Federal
Expression profiles during honeybee caste determination
U.S. Department of Health & Human Services —
Background Depending on their larval environment, female honeybees develop into either queens or workers. As in other polyphenisms, this developmental switch depends... -
Federal
Magnetic stimulation for non-homogeneous biological structures
U.S. Department of Health & Human Services —
Background Magnetic stimulation has gained relatively wide application in studying nervous system structures. This technology has the advantage of reduced excitation... -
Federal
Estimation of genetic distances from human and mouse introns
U.S. Department of Health & Human Services —
Background Using genetic distances measured from exons, it has been observed that the mutation rate is not constant along mammalian chromosomes. Exons constitute only... -
Federal
Twenty-four hour presence of physicians in the ICU
U.S. Department of Health & Human Services —
Intensive-care units (ICUs) must be utilised in the most efficient way. Greater input of intensivists leads to better outcomes and more efficient use of resources.... -
Federal
Traumatic brain injury as a risk factor for Alzheimer disease. Comparison of two retrospective autopsy cohorts with evaluation of ApoE genotype
U.S. Department of Health & Human Services —
Background and Purpose The impact of traumatic brain injury (TBI) on the pathogenesis of Alzheimer disease (AD) is still controversial. The aim of our retrospective... -
Federal
A survey of physicians knowledge regarding awareness of maternal alcohol use and the diagnosis of FAS.
U.S. Department of Health & Human Services —
Background Alcohol is the most widely used drug in the world that is a human teratogen whose use among women of childbearing age has been steadily increasing. It is... -
Federal
Sample size requirements for case-control study designs
U.S. Department of Health & Human Services —
Background Published formulas for case-control designs provide sample sizes required to determine that a given disease-exposure odds ratio is significantly different... -
Federal
Quantitation ofPseudomonas aeruginosain wound biopsy samples: from bacterial culture to rapid `real-time' polymerase chain reaction
U.S. Department of Health & Human Services —
Early diagnosis of wound colonisation or prediction of wound sepsis provides an opportunity for therapeutic intervention. There is need for qualitative and... -
Federal
Estrogen protects against the synergistic toxicity by HIV proteins, methamphetamine and cocaine
U.S. Department of Health & Human Services —
Background Human immunodeficiency virus (HIV) infection continues to increase at alarming rates in drug abusers, especially in women. Drugs of abuse can cause long-... -
Federal
Embryonic stem cells and mice expressing different GFP variants for multiple non-invasive reporter usage within a single animal
U.S. Department of Health & Human Services —
Background Non-invasive autofluorescent reporters have revolutionized lineage labeling in an array of different organisms. In recent years green fluorescent protein... -
Federal
Accessing and distributing EMBL data using CORBA (common object request broker architecture)
U.S. Department of Health & Human Services —
Background: The EMBL Nucleotide Sequence Database is a comprehensive database of DNA and RNA sequences and related information traditionally made available in flat-...
2,009 datasets found