288 datasets found
-
Federal
37-Day microgravity exposure in 16-Week female C57BL/6J mice during the NASA Rodent Research 1 mission is associated with bone loss specific to weight-bearing skeletal sites (femur and vertebrae, micro computed tomography)
National Aeronautics and Space Administration —
Exposure to weightlessness in microgravity and elevated space radiation are associated with rapid bone loss in mammals, but questions remain about their mechanisms of... -
Federal
Combined space stressors induce independent behavioral deficits predicted by early peripheral blood monocytes (Behavioral Assays)
National Aeronautics and Space Administration —
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to... -
Federal
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Frontal Cortex
National Aeronautics and Space Administration —
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how... -
Federal
The impact of deep space radiation on cognitive performance: From biological sex to biomarkers to countermeasures (Flow Cytometry, Synapse from Hippocampus)
National Aeronautics and Space Administration —
In the coming decade, astronauts will travel back to the moon in preparation for future Mars missions. Exposure to galactic cosmic radiation (GCR) is a major obstacle... -
Federal
Effects of heavy particle irradiation and diet on object recognition memory in rats
National Aeronautics and Space Administration —
On long-duration missions to other planets astronauts will be exposed to types and doses of radiation that are not experienced in low earth orbit. Previous research... -
Federal
Spaceflight adaptation requires organ specific alterations in the proteomes of Arabidopsis
National Aeronautics and Space Administration —
Life in spaceflight demonstrates remarkable adaptive processes within the specialized environments of space vehicles which are subject to the myriad of attending and... -
Federal
Light has a principal role in the Arabidopsis transcriptomic response to the spaceflight environment
National Aeronautics and Space Administration —
The Characterizing Arabidopsis Root Attractions (CARA) spaceflight experiment provides comparative transcriptome analyses of plants grown in both light and dark... -
Federal
Proteomics and Transcriptomics analysis of Arabidopsis Seedlings in Microgravity
National Aeronautics and Space Administration —
On Earth plants are constantly exposed to a gravitational field of 1G. Gravity affects a plant in every step of its development. Germinating seedlings orient their... -
Federal
Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Eye, MRI, Optical Coherence Tomography, Tonometry, A-scan)
National Aeronautics and Space Administration —
This ground-based program was intended to address the etiology of visual system structural and functional changes observed in astronauts during both inflight and... -
Federal
Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Subcutaneous Tissue and Subdural Space, Body Temperature and Intracranial Pressure Biotelemetry)
National Aeronautics and Space Administration —
This ground-based program was intended to address the etiology of visual system structural and functional changes observed in astronauts during both inflight and... -
Federal
Impact of simulated microgravity on the growth and proteomic profile of Enterobacter cloacae
National Aeronautics and Space Administration —
The proteomics experiment involved analyzing the protein expression profiles of Enterobacter cloacae under different gravity conditions simulated in High Aspect Ratio... -
Federal
Spatial characterization of microbial communities on multi-species leafy greens grown simultaneously in the Veggie vegetable production systems on the International Space Station VEG-03F
National Aeronautics and Space Administration —
Investigates the microbial communities of plants and Veggie pillow components with culturable and non-culturable methods providing qualitative and quantitative data.... -
Federal
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Dentate Gyrus
National Aeronautics and Space Administration —
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how... -
Federal
Effects of 5-Ion Beam Irradiation and Hindlimb Unloading on Metabolic Pathways in Plasma and Brain of Behaviorally Tested WAG/Rij Rats
National Aeronautics and Space Administration —
A limitation of simulated space radiation studies is that radiation exposure is not the only environmental challenge astronauts face during missions. Therefore, we... -
Federal
Utilizing the KSC Fixation Tube to Conduct Human-Tended Plant Biology Experiments on a Suborbital Spaceflight
National Aeronautics and Space Administration —
Suborbital spaceflights now enable human-tended research investigating short-term gravitational effects in biological systems, eliminating the need for complex... -
Federal
Altered rodent gait characteristics after ~35 days in orbit aboard the International Space Station
National Aeronautics and Space Administration —
The long-term adaptations to microgravity and other spaceflight challenges within the confines of a spacecraft, and readaptations to weight-bearing upon reaching a... -
Federal
Fifteen days of microgravity causes growth in calvaria of mice (STS-131)
National Aeronautics and Space Administration —
Bone growth may occur in spaceflight as a response to skeletal unloading and head-ward fluid shifts. While unloading causes significant loss of bone mass and density... -
Federal
Draft Genome Sequences of novel Agrobacterium genomospecies 3 Associated from the International Space Station
National Aeronautics and Space Administration —
The whole-genome sequences (WGS) of three pathogenic bacterial strains collected from the International Space Station (ISS) were generated and identified as being... -
Federal
Artificial gravity partially protects space-induced neurological deficits in Drosophila melanogaster (Behavior, Climbing)
National Aeronautics and Space Administration —
Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in... -
Federal
Effects of low-dose oxygen ions and protons on cardiac function and structure in male C57BL/6J mice (western blot, histology, and immunohistochemistry)
National Aeronautics and Space Administration —
Purpose: Astronauts traveling beyond low Earth orbit will be exposed to high linear energy transfer charged particles. Because there is concern about the adverse...
288 datasets found