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Federal
Clinical review: Status epilepticus
U.S. Department of Health & Human Services —
Status epilepticus (SE) has an annual incidence exceeding 100,000 cases in the United States alone, of which more than 20% result in death. Thus, increased awareness... -
Federal
Practising evidence-based medicine: the design and implementation of a multidisciplinary team-driven extubation protocol
U.S. Department of Health & Human Services —
Background Evidence from recent literature shows that protocol-directed extubation is a useful approach to liberate patients from mechanical ventilation (MV).... -
Federal
A modification of Representational Difference Analysis, with application to the cloning of a candidate in the Reelin signalling pathway
U.S. Department of Health & Human Services —
Background cDNA-RDA is one of the subtractive cloning techniques used to isolate differentially expressed genes between two complex cDNA populations. In the present... -
Federal
FastGroup: A program to dereplicate libraries of 16S rDNA sequences
U.S. Department of Health & Human Services —
Background Ribosomal 16S DNA sequences are an essential tool for identifying and classifying microbes. High-throughput DNA sequencing now makes it economically... -
Federal
Upregulation of the SERCA-type Ca
U.S. Department of Health & Human Services —
Background Ca2+-ATPases of endoplasmic reticulum (SERCAs) are responsible for maintenance of the micro- to millimolar Ca2+ ion concentrations within the endoplasmic... -
Federal
Identification of cultured isolates of clinically important yeast species using fluorescent fragment length analysis of the amplified internally transcribed rRNA spacer 2 region
U.S. Department of Health & Human Services —
Background The number of patients with yeast infection has increased during the last years. Also the variety of species of clinical importance has increased. Correct... -
Federal
Expression of LRP and MDR1 in locally advanced breast cancer predicts axillary node invasion at the time of rescue mastectomy after induction chemotherapy
U.S. Department of Health & Human Services —
Background: Axillary node status after induction chemotherapy for locally advanced breast cancer has been shown on multivariate analysis to be an independent... -
Federal
Ensuring competency in end-of-life care: controlling symptoms
U.S. Department of Health & Human Services —
Background Palliative medicine is assuming an increasingly important role in patient care. The Education for Physicians in End-of-life Care (EPEC) Project is an... -
Federal
Debate: Are surrogate end-point studies worth the effort?
U.S. Department of Health & Human Services —
Surrogate end-points of cardiovascular disease can provide useful information in cross-sectional, prospective and interventional studies. They provide information on... -
Federal
Debate: Does it matter how you lower blood pressure?
U.S. Department of Health & Human Services —
Whether it matters how pressure is lowered has been debated since antihypertensive drugs proved to prevent cardiovascular events. However, in clinical trials, while... -
Federal
Von Willebrand factor propeptide as a marker of disease activity in systemic sclerosis (scleroderma)
U.S. Department of Health & Human Services —
In 44 consecutive patients with systemic sclerosis (SSc), plasma concentrations of von Willebrand factor (vWf) were higher than those of the vWf propeptide, but the... -
Federal
Effects of chronic inflammatory bowel diseases on left ventricular structure and function: a study protocol
U.S. Department of Health & Human Services —
Background Experimental evidences suggest an increased collagen deposition in inflammatory bowel diseases (IBD). In particular, large amounts of collagen type I, III... -
Federal
Experimental study of the morphine de-addiction properties of
U.S. Department of Health & Human Services —
Background Our aim was to explore the de-addiction properties of Delphinium denudatum Wall. in morphine dependent rats. Methods Charles Foster male albino rats were... -
Federal
Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1beta
U.S. Department of Health & Human Services —
Recent work has established that IL-1β plays a central role in the inflammation and connective tissue destruction observed in both rheumatoid arthritis and... -
Federal
Can we speed up the online publishing process? And who will pay for it, anyway?
U.S. Department of Health & Human Services —
Can we speed up the online publishing process? And who will pay for it, anyway? -
Federal
Calcium dynamics during fertilization in
U.S. Department of Health & Human Services —
Background Of the animals typically used to study fertilization-induced calcium dynamics, none is as accessible to genetics and molecular biology as the model... -
Federal
Rhythmic expression of
U.S. Department of Health & Human Services —
Background Nocturnin was originally identified by differential display as a circadian clock regulated gene with high expression at night in photoreceptors of the... -
Federal
The CRASH trial protocol (Corticosteroid randomisation after significant head injury) [ISRCTN74459797]
U.S. Department of Health & Human Services —
Background Worldwide, millions of people are treated each year for significant head injury. A substantial proportion die, and many more are disabled. If short term... -
Federal
Measurement of microbial activity in soil by colorimetric observation of
U.S. Department of Health & Human Services —
Background Detecting microbial life in extraterrestrial locations is a goal of space exploration because of ecological and health concerns about possible... -
Federal
Norepinephrine-evoked pain in fibromyalgia. A randomized pilot study [ISRCTN70707830]
U.S. Department of Health & Human Services —
Background Fibromyalgia syndrome displays sympathetically maintained pain features such as frequent post-traumatic onset and stimuli-independent pain accompanied by...