288 datasets found
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Federal
Genomic and Proteomic characterization of Aspergillus niger isolated from the International Space Station
National Aeronautics and Space Administration —
Genomic and proteomic characterization of the Aspergillus niger isolate, JSC-093350089, collected from U.S. segment surfaces of the International Space Station (ISS)... -
Federal
Genes Required for Survival in Microgravity Revealed by Genome-Wide Yeast Deletion Collections Cultured during Spaceflight
National Aeronautics and Space Administration —
Spaceflight is a unique environment with profound effects on biological systems including tissue redistribution and musculoskeletal stresses. However, the more subtle... -
Federal
Characterizing Epigenetic Changes in Methylation Mutants (elp2-5 and met1-7) in Response to Spaceflight. [Bisulfite-Seq]
National Aeronautics and Space Administration —
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants’ adaption to environmental... -
Federal
Influence of Sex Hormones on Nervous System and Musculoskeletal Health in Micro and Martian Fractional Gravity in Rat Analogues (Force Plate; Soleus)
National Aeronautics and Space Administration —
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle... -
Federal
T Cell Activation in Microgravity Compared to 1g (Earth's) Gravity
National Aeronautics and Space Administration —
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (uG). Immunosuppression during... -
Federal
RNA-seq analysis of mycobacteria stress response to microgravity
National Aeronautics and Space Administration —
The aim of this work is to determine whether mycobacteria have enhanced virulence during space travel and what mechanisms they use to adapt to microgravity. M.... -
Federal
Multi-modal transcriptional and chromatin accessibility analysis of brains from mice flown on the RR-3 mission
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Sphingomonas Metagenomic assembly
National Aeronautics and Space Administration —
Metagenome Assembled Genome (MAG) of Sphingomonas sanguinis from the International Space Station metagenome -
Federal
SpaceX Inspiration4 Oral, Nasal, and Skin Metagenomic and Metatranscriptomic Microbial Swabs
National Aeronautics and Space Administration —
The SpaceX Inspiration4 mission was a 3-day mission with four private astronauts to low Earth orbit that occurred in September 2021. The crew collected biospecimen... -
Federal
Biological Research in Canisters-16 (BRIC-16): Transcriptomics, Glycomics, and Morphometric photography.
National Aeronautics and Space Administration —
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse adrenal gland transcriptomic, proteomic, and epigenomic data
National Aeronautics and Space Administration —
NASA's Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Transcriptomics analysis of etiolated Arabidopsis thaliana seedlings in response to microgravity
National Aeronautics and Space Administration —
Gene expression profile of two-week-old etiolated Arabidopsis seedlings under microgravity on board space flight BRIC16 were compared with ground grown control in... -
Federal
Microbial Observatory (ISS-MO): Molecular characterization of Bacillus issensis, sp. nov., isolated from various quarters of the International Space Station
National Aeronautics and Space Administration —
As part of an ongoing effort to catalogue microbial communities inhabiting the International Space Station (ISS) crew-associated environmental samples were collected... -
Federal
Transcriptomic response of Drosophila melanogaster pupae developed in hypergravity
National Aeronautics and Space Administration —
Physical forces greatly influence the growth and function of an organism. Altered gravity can perturb normal development and induce corresponding changes in gene... -
Federal
Biomolecule Sequencer
National Aeronautics and Space Administration —
Technology demonstration of a nanopore sequencer operating aboard the ISS in comparison with the same sequencer on the ground. -
Federal
Biological and Metabolic Response in STS-135 Space-flown Mouse Skin
National Aeronautics and Space Administration —
Changes in gene expression profiles implicated in oxidative stress and in ECM remodeling in mouse skin were examined after space flight. The metabolic effects of... -
Federal
Effects of spaceflight on the immunoglobulin repertoire of unimmunized C57BL/6 mice
National Aeronautics and Space Administration —
Spaceflight has been shown to suppress the adaptive immune response, altering the distribution and function of lymphocyte populations. B lymphocytes express highly... -
Federal
Comparison of the spaceflight transcriptome of four commonly used Arabidopsis thaliana ecotypes
National Aeronautics and Space Administration —
This experiment compared the spaceflight transcriptomes of four commonly used natural variants (ecotypes) of Arabidopsis thaliana using RNAseq. In nature, Arabidopsis... -
Federal
Immediate Transcriptional Changes in Response to High Dose Radiation Exposure
National Aeronautics and Space Administration —
One of the most likely risks astronauts on long duration space missions face is exposure to ionizing radiation associated with highly energetic and charged heavy... -
Federal
Microbial Observatory (ISS-MO): Draft Genome Sequence of two Aspergillus fumigatus Strains Isolated from the International Space Station
National Aeronautics and Space Administration —
Aspergillus fumigatus is a saprophytic, filamentous fungus that is ubiquitous outdoors (soil, decaying vegetation) and indoors (hospitals, simulated closed habitats,...
288 datasets found