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Federal
Characterization of Biofilm Formation, Growth, and Gene Expression on Different Materials and Environmental Conditions in Microgravity (Gene expression of Pseudomonas aeruginosa biofilms)
National Aeronautics and Space Administration —
Microorganisms' natural ability to live as organized multicellular communities – also known as biofilms – provides them with unique survival advantages. For instance,... -
Federal
Drosophila parasitoids go to space: Unexpected and differential effects of spaceflight on hosts and their parasitoids - Wasp Leptopilina boulardi 17 data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Spatial characterization of microbial communities on multi-species leafy greens grown simultaneously in the Veggie vegetable production systems on the International Space Station VEG-03D
National Aeronautics and Space Administration —
Investigates the microbial communities of plants and Veggie pillow components with culturable and non-culturable methods providing qualitative and quantitative data.... -
Federal
Apollo 17 Challenge System - Seed Germination (Cabbage, Brussel Sprouts, Radish and Lettuce)
National Aeronautics and Space Administration —
Analyses of effects of lunar materials on plants: This study was designed to determine if lunar material can cause disease in plants grown under controlled conditions... -
Federal
ISS Enterobacteriales Genomes
National Aeronautics and Space Administration —
The microbial tracking-1 (MT-1) investigation allowed the characterization of the microbial population aboard the International Space Station (ISS). -
Federal
Modeling cellular responses to serum and vitamin D in microgravity using a human kidney microphysiological system
National Aeronautics and Space Administration —
The microgravity environment aboard the International Space Station (ISS) provides a unique stressor that can help understand underlying cellular and molecular... -
Federal
Predicting how varying moisture conditions impact the microbiome of dust collected from the International Space Station (ISS)
National Aeronautics and Space Administration —
On Earth, people spend 90% of their time indoors where dust and moisture can facilitate rapid microbial growth, especially fungi. The International Space Station is a... -
Federal
Space environmental factor impacts upon murine colon microbiota and mucosal homeostasis
National Aeronautics and Space Administration —
We report how high and low linear energy transfer (LET) radiation, microgravity, and elevated dietary iron affect colon microbiota (determined by 16S rDNA... -
Federal
STS-135 Liver Transcriptomics
National Aeronautics and Space Administration —
Mice were flown onboard STS-135 and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples were... -
Federal
Microbial Observatory (ISS-MO): Study of BSL-2 bacterial isolates from the International Space Station
National Aeronautics and Space Administration —
In an on-going Microbial Observatory experimental investigation on the International Space Station (ISS) multiple bacterial isolates of Biosafety Level 2 (BSL-2) were... -
Federal
Dissecting Low Atmospheric Pressure Stress: Transcriptome Responses to the Components of Hypobaria in Arabidopsis [Experiment 1]
National Aeronautics and Space Administration —
Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology, yet the apparent components of hypobaria are stresses... -
Federal
Response to Low Shear Modeled Microgravity Indicates Translation of Lactobacillus acidophilus ATCC 4356 Benefits to Spaceflight
National Aeronautics and Space Administration —
The introduction of generally recognized as safe (GRAS) probiotic microbes into the spaceflight food system has the potential for use as a safe, non-invasive, daily... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse left gastrocnemius muscle transcriptomic, proteomic, and epigenomic data
National Aeronautics and Space Administration —
NASA's Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Validation of Methods to Assess the Immunoglobulin Gene Repertoire in Tissues Obtained from Mice on the International Space Station
National Aeronautics and Space Administration —
Spaceflight is known to affect immune cell populations. In particular, splenic B-cell numbers decrease during spaceflight and in ground-based physiological models.... -
Federal
RNA seq of tumors derived from irradiated versus sham hosts transplanted with Trp53 null mammary tissue and fed either Control diet versus Caffeic Acid Phenethyl Ester (CAPE) diet.
National Aeronautics and Space Administration —
Irradiated hosts gave rise to significantly more Trp53 null mammary cancers that grew more rapidly than those in sham-irradiated mice and exhibited an... -
Federal
Comparative Genomic Analysis of Klebsiella Exposed to Various Space Conditions at the International Space Station
National Aeronautics and Space Administration —
Due to the bacteria's evolved resistance to radiation, Klebsiella poses a great threat to not only planetary protection, but also to the integrity of future... -
Federal
Genomic Characterization and Virulence Potential of Two Fusarium oxysporum Isolates Cultured from the International Space Station
National Aeronautics and Space Administration —
Two isolates of Fusarium oxysporum, ISS-F3 and ISS-F4, were cultured from the dining table on the International Space Station (ISS). Genomic analyses using EF-1α... -
Federal
Alternative splicing regulates the physiological adaptation of the mouse hind limb postural and phasic muscles to microgravity
National Aeronautics and Space Administration —
We sought to comprehensively elucidate the transcriptomic underpinnings of microgravity-induced muscle phenotypes in mice by evaluating both differential gene...