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2 datasets found

Federal

Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda2 protein

U.S. Department of Health & Human Services —

Background The reovirus λ2 protein catalyzes mRNA capping, that is, addition of a guanosine to the 5' end of each transcript in a 5'-to-5' orientation, as well as...
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Federal

mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships

U.S. Department of Health & Human Services —

The 5'-terminal cap structure plays an important role in many aspects of mRNA metabolism. Capping enzymes encoded by viruses and pathogenic fungi are attractive...
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2 datasets found

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