5 datasets found
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Federal
Hepatic glucokinase promoter polymorphism is associated with hepatic insulin resistance in Asian Indians.
U.S. Department of Health & Human Services —
Background The role of glucokinase (GCK) in the pathogenesis of maturity-onset diabetes of the young is well established. However, its role in the common form of type... -
Federal
The vitamin D receptor polymorphism in the translation initiation codon is a risk factor for insulin resistance in glucose tolerant Caucasians
U.S. Department of Health & Human Services —
Background Although vitamin D receptor (VDR) polymorphisms have been shown to be associated with abnormal glucose metabolism, the reported polymorphisms are unlikely... -
Federal
TheG-308Avariant of the Tumor Necrosis Factor-α (TNF-α) gene is not associated with obesity, insulin resistance and body fat distribution
U.S. Department of Health & Human Services —
Tumor Necrosis Factor-α (TNF-α) has been implicated in the pathogenesis of insulin resistance and obesity. The increased expression of TNF-α in adipose tissue has... -
Federal
The A54T polymorphism at the intestinal fatty acid binding protein 2 is associated with insulin resistance in glucose tolerant Caucasians
U.S. Department of Health & Human Services —
Background An A54T polymorphism at the fatty acid binding protein 2 (FABP2) locus was found to be associated with insulin resistance in non-diabetic Pima Indians. To... -
Federal
Clinical significance of cardiovascular dysmetabolic syndrome
U.S. Department of Health & Human Services —
Although diabetes mellitus is predominantly a metabolic disorder, recent data suggest that it is as much a vascular disorder. Cardiovascular complications are the...
5 datasets found