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Federal
Reconstitution of licensed replication origins on
U.S. Department of Health & Human Services —
Background In order to ensure precise chromosome duplication, eukaryotes "license" their replication origins during late mitosis and early G1 by assembling complexes... -
Federal
Stress responses and replication of plasmids in bacterial cells
U.S. Department of Health & Human Services —
Plasmids, DNA (or rarely RNA) molecules which replicate in cells autonomously (independently of chromosomes) as non-essential genetic elements, play important roles... -
Federal
Multiple redundant sequence elements within the fission yeast
U.S. Department of Health & Human Services —
Background Some origins in eukaryotic chromosomes fire more frequently than others. In the fission yeast, Schizosaccharomyces pombe, the relative firing frequencies... -
Federal
Asymmetric directional mutation pressures in bacteria
U.S. Department of Health & Human Services —
When there are no strand-specific biases in mutation and selection rates between the two strands of DNA, the average nucleotide composition is theoretically expected...