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Federal
PKQuest: a general physiologically based pharmacokinetic model. Introduction and application to propranolol
U.S. Department of Health & Human Services —
Background A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been... -
Federal
Endovascular treatment of huge saccular abdominal aortic aneurysm in a young Behcet patient: mid-term result
U.S. Department of Health & Human Services —
Background Abdominal aortic aneurysm formation is among the arterial complications of Behcet's disease. Weakness and fragility of aortic walls leads to the... -
Federal
Mouse skin passage of a
U.S. Department of Health & Human Services —
Background Streptolysin S (SLS), the oxygen-stable hemolysin of Streptococcus pyogenes, has recently been shown to be encoded by the sagA/pel gene. Mutants lacking... -
Federal
Compound 526722: 2-(2-(2-(2-nonyloxy-ethoxy)-ethoxy)-ethoxy)-ethanol, TMS
U.S. Department of Health & Human Services —
Chemical compound data from PubChem database. IUPAC Name: trimethyl-[2-[2-[2-(2-nonoxyethoxy)ethoxy]ethoxy]ethoxy]silane. Molecular Formula: C20H44O5Si. Molecular... -
Federal
Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer – a phase II study
U.S. Department of Health & Human Services —
Background 5-fluorouracil remains the standard therapy for patients with advanced/metastatic colorectal cancer. Pre-clinical studies have demonstrated the biological... -
Federal
Compound 525245: N''-(4-bromo-phenyl)-N,N,N',N'-tetramethyl-guanidine
U.S. Department of Health & Human Services —
Chemical compound data from PubChem database. IUPAC Name: 2-(4-bromophenyl)-1,1,3,3-tetramethylguanidine. Molecular Formula: C11H16BrN3. Molecular Weight: 270.17.... -
Federal
Patent AT-E400587-T1: [Translated] ANTIBODIES DIRECTED AGAINST THE PROSTATE STEM CELL ANTIGEN (PSCA) AND THEIR USE
U.S. Department of Health & Human Services —
The invention provides isolated anti-prostate stem cell antigen (PSCA) antibodies that internalize upon binding to PSCA on a mammalian in vivo. The invention also... -
Federal
Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction
U.S. Department of Health & Human Services —
In the present study, we searched for mutant PTEN transcripts in aggressive rheumatoid arthritis synovial fibroblasts (RA-SF) and studied the expression of PTEN in... -
Federal
Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis
U.S. Department of Health & Human Services —
Background NF1 refers to type 1 neurofibromatosis syndrome, which has been linked with mutations of the large NF1 gene. NF1 tumor suppressor protein, neurofibromin,... -
Federal
Patent AT-E400168-T1: [Translated] AGRICULTURAL PROCESSING MACHINE
U.S. Department of Health & Human Services —
The seed drill has a central frame (1), on which swiveling front (4) and rear (3) frames are mounted. These are supported by wheels (11) connected to disks (13) and... -
Federal
Compound 526070: 1-Hexadecanol, 14-methyl, TMS
U.S. Department of Health & Human Services —
Chemical compound data from PubChem database. IUPAC Name: trimethyl(14-methylhexadecoxy)silane. Molecular Formula: C20H44OSi. Molecular Weight: 328.6. This dataset... -
Federal
Substance 866155: MLS000083616
U.S. Department of Health & Human Services —
Chemical substance data from PubChem database. This dataset contains comprehensive chemical information including structural data, physical properties, and biological... -
Federal
Compound 526218: 1,9-Dibromo-3,7-dichloro-dibenzo-p-dioxin
U.S. Department of Health & Human Services —
Chemical compound data from PubChem database. IUPAC Name: 1,9-dibromo-3,7-dichlorodibenzo-p-dioxin. Molecular Formula: C12H4Br2Cl2O2. Molecular Weight: 410.9. This... -
Federal
Debate: A subversive view of subsets - a dissident clinician's opinion
U.S. Department of Health & Human Services —
Clinical trialists and statisticians are very wary of subgroup analysis, for good reasons. Clinicians have to deal with situations in which subgroups of patients... -
Federal
An efficient method to successively introduce transgenes into a given genomic locus in the mouse
U.S. Department of Health & Human Services —
Background Expression of transgenes in mice requires transcriptional regulatory elements that direct expression in a chosen cell type. Unfortunately, the availability... -
Federal
Substance 864269: MLS000041610
U.S. Department of Health & Human Services —
Chemical substance data from PubChem database. This dataset contains comprehensive chemical information including structural data, physical properties, and biological... -
Federal
Patent AT-E400871-T1: [Translated] MULTIMODAL DATA ENTRY
U.S. Department of Health & Human Services —
The invention is directed to an apparatus for controlling at least one electronic device, comprising a haptic input means, an acoustic input means, and a switching... -
Federal
Patent AT-E400611-T1: [Translated] COMPOSITION COEXTRUDABLE WITH PVDF
U.S. Department of Health & Human Services —
Chemical patent from PubChem database. Patent Number: AT-E400611-T1. Title: Sustained Release Formulation. Filing Date: 2004-08-11. Inventors: Rodriguez, Juan, White,... -
Federal
Patent AT-E401383-T1: [Translated] CHIRAL PHOTOISOMERISABLE COMPOUNDS
U.S. Department of Health & Human Services —
The invention relates to chiral photoisomerizable compounds of formula (I) wherein X1, X2, X3, X4, X5 and X6 have the meanings given in claim 1 , to liquid... -
Federal
Compound 528060: L-Isoleucine, N-(tert-butyldimethylsilyl)-, tert-butyldimethylsilyl ester
U.S. Department of Health & Human Services —
Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-[[tert-butyl(dimethyl)silyl]amino]-3-methylpentanoate. Molecular Formula:...